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- W2084238081 abstract "The cDNA of turkey interleukin-18 (IL18) was cloned, initially using oligonucleotide primers based on the sequence of the chicken IL18 gene. The coding regions of the turkey and chicken IL18 genes are highly conserved (96.1% nucleotide identical and 97.4% amino acid identical). The 3' UTR of the turkey IL18 mRNA contains two 'instability' motifs and a canonical polyadenylation site, as compared to the chicken IL18 mRNA which contains only one instability motif and lacks a canonical polyadenylation site. Phylogenetic analysis shows that turkey and chicken IL18 have diverged to a less extent than IL18 from closely related mammalian species. We predict that turkey and chicken IL18 will cross-react in functional assays." @default.
- W2084238081 created "2016-06-24" @default.
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- W2084238081 date "2002-10-01" @default.
- W2084238081 modified "2023-10-10" @default.
- W2084238081 title "Turkey and chicken interleukin-18 (IL18) share high sequence identity, but have different polyadenylation sites in their 3′ UTR" @default.
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- W2084238081 doi "https://doi.org/10.1016/s0145-305x(02)00024-1" @default.
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