FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2084253661> ?p ?o ?g. }

• W2084253661 endingPage "150" @default.
• W2084253661 startingPage "140" @default.
• W2084253661 abstract "Background Previous studies showed that moderate and severe acute cardiac rejection (AR) but not mild AR is associated with significant myocardial acoustic changes. This study examines whether serial measurements of end-diastolic two-dimensional integrated backscatter (2D-IB) enhance the diagnostic potential of ultrasonic tissue analysis in AR. Methods and Results Serial endomyocardial biopsies, conventional echocardiograms, and parasternal long-axis radiofrequency signals for determination of posterior wall and septal 2D-IB were performed in 52 transplant patients. Histology showed no AR in 155 biopsy samples, AR grade 1A in 25, AR grade 1B/2 in 27, and AR grade 3A/3B in 13. Whereas no significant 2D-IB changes occurred between AR-free studies and during AR grade 1A, posterior wall and septal 2D-IB increased during AR grade 1B/2 from −47.80±4.36 to −42.97±5.11 dB and from −36.72±7.45 to −32.52±7.98 dB ( P <.001 and P <.05, respectively) and during AR grade 3A/3B from −47.96±4.74 to −38.25±5.32 dB and from −37.92±5.87 to −31.01±4.62 dB ( P <.001 and P <.01, respectively). Changes in posterior wall and septal 2D-IB were greater during AR grade 3A/3B than during AR grade 1B/2 ( P <.01 and P <.05). Increases of 1.5 dB in posterior wall or septal 2D-IB indicated AR grades ≥1B with sensitivities of 88% and 83% and specificities of 89% and 85%; posterior wall and septal 2D-IB increases of 5.5 and 3.8 dB identified AR grades ≥3A with sensitivities of 92% and 79% and specificities of 90% and 84%. Although a weak inverse correlation between posterior wall and septal 2D-IB changes and posterior wall and septal thickening ( r =.41 and r =.39, both P <.001) and fractional diameter shortening ( r =.35, P <.001) was found, significant 2D-IB increases also occurred in some rejecting patients with unaltered contraction. Conclusions Increases in end-diastolic posterior wall and septal 2D-IB in serial studies permit reliable identification not only of moderate and severe AR but also of mild AR. Because 2D-IB increases significantly more in AR with myocyte damage than without such damage, an estimate of AR severity appears feasible. Significant myocardial acoustic changes during AR may occur independently of changes in contractile performance." @default.
• W2084253661 created "2016-06-24" @default.
• W2084253661 creator A5027677803 @default.
• W2084253661 creator A5032973221 @default.
• W2084253661 creator A5039105114 @default.
• W2084253661 creator A5045819021 @default.
• W2084253661 creator A5049098990 @default.
• W2084253661 creator A5063174072 @default.
• W2084253661 creator A5073072840 @default.
• W2084253661 creator A5074002015 @default.
• W2084253661 creator A5088509546 @default.
• W2084253661 date "1997-01-07" @default.
• W2084253661 modified "2023-09-26" @default.
• W2084253661 title "Recognition of Acute Cardiac Allograft Rejection From Serial Integrated Backscatter Analyses in Human Orthotopic Heart Transplant Recipients" @default.
• W2084253661 cites W1970011466 @default.
• W2084253661 cites W1973624668 @default.
• W2084253661 cites W1980163954 @default.
• W2084253661 cites W1983446901 @default.
• W2084253661 cites W2028454592 @default.
• W2084253661 cites W2038202546 @default.
• W2084253661 cites W2040180547 @default.
• W2084253661 cites W2048402571 @default.
• W2084253661 cites W2066436313 @default.
• W2084253661 cites W2069715825 @default.
• W2084253661 cites W2086390336 @default.
• W2084253661 cites W2146237303 @default.
• W2084253661 cites W2291450029 @default.
• W2084253661 doi "https://doi.org/10.1161/01.cir.95.1.140" @default.
• W2084253661 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8994429" @default.
• W2084253661 hasPublicationYear "1997" @default.
• W2084253661 type Work @default.
• W2084253661 sameAs 2084253661 @default.
• W2084253661 citedByCount "60" @default.
• W2084253661 countsByYear W20842536612012 @default.
• W2084253661 countsByYear W20842536612013 @default.
• W2084253661 countsByYear W20842536612014 @default.
• W2084253661 countsByYear W20842536612015 @default.
• W2084253661 countsByYear W20842536612016 @default.
• W2084253661 countsByYear W20842536612020 @default.
• W2084253661 crossrefType "journal-article" @default.
• W2084253661 hasAuthorship W2084253661A5027677803 @default.
• W2084253661 hasAuthorship W2084253661A5032973221 @default.
• W2084253661 hasAuthorship W2084253661A5039105114 @default.
• W2084253661 hasAuthorship W2084253661A5045819021 @default.
• W2084253661 hasAuthorship W2084253661A5049098990 @default.
• W2084253661 hasAuthorship W2084253661A5063174072 @default.
• W2084253661 hasAuthorship W2084253661A5073072840 @default.
• W2084253661 hasAuthorship W2084253661A5074002015 @default.
• W2084253661 hasAuthorship W2084253661A5088509546 @default.
• W2084253661 hasConcept C126322002 @default.
• W2084253661 hasConcept C126894567 @default.
• W2084253661 hasConcept C164705383 @default.
• W2084253661 hasConcept C23036609 @default.
• W2084253661 hasConcept C2775934546 @default.
• W2084253661 hasConcept C2989005 @default.
• W2084253661 hasConcept C3020352339 @default.
• W2084253661 hasConcept C57742111 @default.
• W2084253661 hasConcept C57900726 @default.
• W2084253661 hasConcept C71924100 @default.
• W2084253661 hasConcept C84393581 @default.
• W2084253661 hasConceptScore W2084253661C126322002 @default.
• W2084253661 hasConceptScore W2084253661C126894567 @default.
• W2084253661 hasConceptScore W2084253661C164705383 @default.
• W2084253661 hasConceptScore W2084253661C23036609 @default.
• W2084253661 hasConceptScore W2084253661C2775934546 @default.
• W2084253661 hasConceptScore W2084253661C2989005 @default.
• W2084253661 hasConceptScore W2084253661C3020352339 @default.
• W2084253661 hasConceptScore W2084253661C57742111 @default.
• W2084253661 hasConceptScore W2084253661C57900726 @default.
• W2084253661 hasConceptScore W2084253661C71924100 @default.
• W2084253661 hasConceptScore W2084253661C84393581 @default.
• W2084253661 hasIssue "1" @default.
• W2084253661 hasLocation W20842536611 @default.
• W2084253661 hasLocation W20842536612 @default.
• W2084253661 hasOpenAccess W2084253661 @default.
• W2084253661 hasPrimaryLocation W20842536611 @default.
• W2084253661 hasRelatedWork W1967941527 @default.
• W2084253661 hasRelatedWork W2031133619 @default.
• W2084253661 hasRelatedWork W2050053535 @default.
• W2084253661 hasRelatedWork W2089162564 @default.
• W2084253661 hasRelatedWork W2143369845 @default.
• W2084253661 hasRelatedWork W2392413698 @default.
• W2084253661 hasRelatedWork W2399703909 @default.
• W2084253661 hasRelatedWork W2404753647 @default.
• W2084253661 hasRelatedWork W3014718631 @default.
• W2084253661 hasRelatedWork W3043622045 @default.
• W2084253661 hasVolume "95" @default.
• W2084253661 isParatext "false" @default.
• W2084253661 isRetracted "false" @default.
• W2084253661 magId "2084253661" @default.
• W2084253661 workType "article" @default.