Matches in SemOpenAlex for { <https://semopenalex.org/work/W2084287421> ?p ?o ?g. }
- W2084287421 endingPage "2258" @default.
- W2084287421 startingPage "2250" @default.
- W2084287421 abstract "Primary pituitary cell cultures are an important tool for understanding pituitary hormone gene expression. In the course of study of pituitary cell cultures from nonhuman adult male primates, pituitary secretory cells were noted to be rapidly overgrown by epithelioid cells with the morphological, immunocytochemical, and proliferative characteristics of folliculostellate cells. Using competitive RT-PCR assays, follistatin mRNA levels were found to increase 4-fold as folliculostellate cells proliferated with time in culture, whereas FSH-beta mRNA and FSH secretion were suppressed. Follistatin gene expression was stimulated by activin-A and pituitary adenylate cyclase-activating polypeptide but not by [D-Trp(6)]-GnRH ethylamide. Testosterone (T) also increased follistatin mRNA levels and follistatin protein secretion. FSH-beta mRNA was stimulated by [D-Trp(6)]-GnRH ethylamide and activin but was suppressed by T. The reciprocal relationship between follistatin and FSH-beta mRNA levels as folliculostellate cells proliferate with time in culture implies a role for folliculostellate cells in the follistatin-activin system in primates. The actions of GnRH and T on follistatin and FSH-beta mRNA levels in these cultures were opposite to effects observed in pituitary cultures from rats and identify species differences in the control of FSH production that may be folliculostellate cell-related." @default.
- W2084287421 created "2016-06-24" @default.
- W2084287421 creator A5031050928 @default.
- W2084287421 creator A5072492344 @default.
- W2084287421 creator A5087822746 @default.
- W2084287421 creator A5089503656 @default.
- W2084287421 date "2002-06-01" @default.
- W2084287421 modified "2023-10-17" @default.
- W2084287421 title "Paracrine Regulation of FSH by Follistatin in Folliculostellate Cell-Enriched Primate Pituitary Cell Cultures" @default.
- W2084287421 cites W1530446855 @default.
- W2084287421 cites W1866642200 @default.
- W2084287421 cites W1963668662 @default.
- W2084287421 cites W1966940644 @default.
- W2084287421 cites W1968823656 @default.
- W2084287421 cites W1970413305 @default.
- W2084287421 cites W1970437704 @default.
- W2084287421 cites W1973872148 @default.
- W2084287421 cites W1974765031 @default.
- W2084287421 cites W1975304932 @default.
- W2084287421 cites W1975870493 @default.
- W2084287421 cites W1979560009 @default.
- W2084287421 cites W1979834347 @default.
- W2084287421 cites W1980785667 @default.
- W2084287421 cites W1981591766 @default.
- W2084287421 cites W1987063529 @default.
- W2084287421 cites W1988097469 @default.
- W2084287421 cites W1991825810 @default.
- W2084287421 cites W1993538394 @default.
- W2084287421 cites W1999096385 @default.
- W2084287421 cites W1999940194 @default.
- W2084287421 cites W2000484846 @default.
- W2084287421 cites W2003266245 @default.
- W2084287421 cites W2006601522 @default.
- W2084287421 cites W2014553875 @default.
- W2084287421 cites W2017177010 @default.
- W2084287421 cites W2023541046 @default.
- W2084287421 cites W2026774638 @default.
- W2084287421 cites W2029587704 @default.
- W2084287421 cites W2033212588 @default.
- W2084287421 cites W2033274252 @default.
- W2084287421 cites W2033755926 @default.
- W2084287421 cites W2034167269 @default.
- W2084287421 cites W2035558490 @default.
- W2084287421 cites W2044160710 @default.
- W2084287421 cites W2047030030 @default.
- W2084287421 cites W2049839497 @default.
- W2084287421 cites W2050602280 @default.
- W2084287421 cites W2050775671 @default.
- W2084287421 cites W2053653047 @default.
- W2084287421 cites W2054139793 @default.
- W2084287421 cites W2056679265 @default.
- W2084287421 cites W2066871164 @default.
- W2084287421 cites W2067589401 @default.
- W2084287421 cites W2069359083 @default.
- W2084287421 cites W2080424286 @default.
- W2084287421 cites W2091446981 @default.
- W2084287421 cites W2091602148 @default.
- W2084287421 cites W2091779202 @default.
- W2084287421 cites W2092292088 @default.
- W2084287421 cites W2093509517 @default.
- W2084287421 cites W2094231485 @default.
- W2084287421 cites W2096563287 @default.
- W2084287421 cites W2100231662 @default.
- W2084287421 cites W2107757798 @default.
- W2084287421 cites W2121080380 @default.
- W2084287421 cites W2134812217 @default.
- W2084287421 cites W2147463574 @default.
- W2084287421 cites W2148866023 @default.
- W2084287421 cites W2152496892 @default.
- W2084287421 cites W2162243883 @default.
- W2084287421 cites W2164063741 @default.
- W2084287421 cites W2169230760 @default.
- W2084287421 cites W2170260095 @default.
- W2084287421 cites W2219802494 @default.
- W2084287421 cites W2325666068 @default.
- W2084287421 cites W55458884 @default.
- W2084287421 doi "https://doi.org/10.1210/endo.143.6.8857" @default.
- W2084287421 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12021189" @default.
- W2084287421 hasPublicationYear "2002" @default.
- W2084287421 type Work @default.
- W2084287421 sameAs 2084287421 @default.
- W2084287421 citedByCount "34" @default.
- W2084287421 countsByYear W20842874212012 @default.
- W2084287421 countsByYear W20842874212014 @default.
- W2084287421 countsByYear W20842874212015 @default.
- W2084287421 countsByYear W20842874212016 @default.
- W2084287421 countsByYear W20842874212017 @default.
- W2084287421 countsByYear W20842874212018 @default.
- W2084287421 countsByYear W20842874212019 @default.
- W2084287421 crossrefType "journal-article" @default.
- W2084287421 hasAuthorship W2084287421A5031050928 @default.
- W2084287421 hasAuthorship W2084287421A5072492344 @default.
- W2084287421 hasAuthorship W2084287421A5087822746 @default.
- W2084287421 hasAuthorship W2084287421A5089503656 @default.
- W2084287421 hasBestOaLocation W20842874211 @default.
- W2084287421 hasConcept C104317684 @default.
- W2084287421 hasConcept C105580179 @default.
- W2084287421 hasConcept C126322002 @default.