FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2084328300> ?p ?o ?g. }

• W2084328300 endingPage "260" @default.
• W2084328300 startingPage "252" @default.
• W2084328300 abstract "Previous studies of postmortem neurochemical markers in severe psychiatric disorders have been carried out on different brain collections, making it difficult to compare results.One hundred RNA, protein, and other neurochemical markers were assessed in a single set of 60 postmortem brains (15 each with schizophrenia, bipolar disorder, major depression without psychosis, and unaffected control subjects) in relation to seven neurochemical systems. Quantitative measures of continuous variables for prefrontal, hippocampus, anterior cingulate, superior temporal cortex, or a combination of these were analyzed from published and unpublished studies by 56 research groups.Before correcting for multiple comparisons, 23% of markers (23/100) were abnormal in one or more regions, with most indicating decreased expression. The largest percentage were associated with the developmental/synaptic (10/22) and gamma-aminobutyric acid (GABA; 3/7) systems. Bipolar disorder (20) and schizophrenia (19) had the most abnormalities, with a 65% overlap. When all brain areas were considered together and corrected for multiple comparisons, reelin, parvalbumin, and GAD67 were the most abnormal.Confirming other studies, the GABA and developmental/synaptic neurochemical systems are promising areas for research on schizophrenia and bipolar disorder. Research should include tissue from both diseases, and additional brain areas should be assessed." @default.
• W2084328300 created "2016-06-24" @default.
• W2084328300 creator A5000843014 @default.
• W2084328300 creator A5010887562 @default.
• W2084328300 creator A5041365154 @default.
• W2084328300 creator A5058188685 @default.
• W2084328300 creator A5060517208 @default.
• W2084328300 creator A5075950846 @default.
• W2084328300 date "2005-02-01" @default.
• W2084328300 modified "2023-10-16" @default.
• W2084328300 title "Neurochemical markers for schizophrenia, bipolar disorder, and major depression in postmortem brains" @default.
• W2084328300 cites W1211088797 @default.
• W2084328300 cites W1948643290 @default.
• W2084328300 cites W1960099260 @default.
• W2084328300 cites W1963490696 @default.
• W2084328300 cites W1967450410 @default.
• W2084328300 cites W1967982538 @default.
• W2084328300 cites W1968700646 @default.
• W2084328300 cites W1969171865 @default.
• W2084328300 cites W1975996377 @default.
• W2084328300 cites W1977998932 @default.
• W2084328300 cites W1978703935 @default.
• W2084328300 cites W1979219206 @default.
• W2084328300 cites W1981241060 @default.
• W2084328300 cites W1985339794 @default.
• W2084328300 cites W1986763467 @default.
• W2084328300 cites W1992876329 @default.
• W2084328300 cites W1995897528 @default.
• W2084328300 cites W2003806209 @default.
• W2084328300 cites W2004881650 @default.
• W2084328300 cites W2006261940 @default.
• W2084328300 cites W2007270186 @default.
• W2084328300 cites W2007742115 @default.
• W2084328300 cites W2012725087 @default.
• W2084328300 cites W2015268580 @default.
• W2084328300 cites W2016712906 @default.
• W2084328300 cites W2016946796 @default.
• W2084328300 cites W2017067141 @default.
• W2084328300 cites W2021712507 @default.
• W2084328300 cites W2022039071 @default.
• W2084328300 cites W2022428482 @default.
• W2084328300 cites W2027829376 @default.
• W2084328300 cites W2029096714 @default.
• W2084328300 cites W2030538289 @default.
• W2084328300 cites W2030564379 @default.
• W2084328300 cites W2032208151 @default.
• W2084328300 cites W2032529587 @default.
• W2084328300 cites W2038331502 @default.
• W2084328300 cites W2039895645 @default.
• W2084328300 cites W2042369309 @default.
• W2084328300 cites W2042773138 @default.
• W2084328300 cites W2045484738 @default.
• W2084328300 cites W2046358782 @default.
• W2084328300 cites W2048447433 @default.
• W2084328300 cites W2054859366 @default.
• W2084328300 cites W2056646300 @default.
• W2084328300 cites W2060642455 @default.
• W2084328300 cites W2065475795 @default.
• W2084328300 cites W2076484114 @default.
• W2084328300 cites W2078446073 @default.
• W2084328300 cites W2080571615 @default.
• W2084328300 cites W2088720667 @default.
• W2084328300 cites W2093248761 @default.
• W2084328300 cites W2097142850 @default.
• W2084328300 cites W2097266643 @default.
• W2084328300 cites W2097960662 @default.
• W2084328300 cites W2104520529 @default.
• W2084328300 cites W2112675213 @default.
• W2084328300 cites W2116835712 @default.
• W2084328300 cites W2124578903 @default.
• W2084328300 cites W2128284178 @default.
• W2084328300 cites W2134441514 @default.
• W2084328300 cites W2138953643 @default.
• W2084328300 cites W2149059160 @default.
• W2084328300 cites W2156026059 @default.
• W2084328300 cites W2156305088 @default.
• W2084328300 cites W2162916231 @default.
• W2084328300 cites W2170696995 @default.
• W2084328300 cites W2171865323 @default.
• W2084328300 cites W2284323937 @default.
• W2084328300 cites W2886587096 @default.
• W2084328300 cites W44954597 @default.
• W2084328300 doi "https://doi.org/10.1016/j.biopsych.2004.10.019" @default.
• W2084328300 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15691526" @default.
• W2084328300 hasPublicationYear "2005" @default.
• W2084328300 type Work @default.
• W2084328300 sameAs 2084328300 @default.
• W2084328300 citedByCount "399" @default.
• W2084328300 countsByYear W20843283002012 @default.
• W2084328300 countsByYear W20843283002013 @default.
• W2084328300 countsByYear W20843283002014 @default.
• W2084328300 countsByYear W20843283002015 @default.
• W2084328300 countsByYear W20843283002016 @default.
• W2084328300 countsByYear W20843283002017 @default.
• W2084328300 countsByYear W20843283002018 @default.
• W2084328300 countsByYear W20843283002019 @default.
• W2084328300 countsByYear W20843283002020 @default.
• W2084328300 countsByYear W20843283002021 @default.

• next