FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2084355267> ?p ?o ?g. }

• W2084355267 endingPage "322" @default.
• W2084355267 startingPage "311" @default.
• W2084355267 abstract "Myocardial hypertrophy often develops in response to hypertension, and it is causal to and an independent predictor of heart failure. Several risk factors modify the progression of hypertrophy, the associated progressive impairment of myocardial function, and eventually the transition to overt congestive heart failure. The aim of the present study was to investigate the effects of smoking on the progression of pressure-dependent myocardial hypertrophy.Spontaneously hypertensive rats (SHR) were used as a model for pressure-dependent hypertrophy. SHR were exposed to mainstream smoke from the Kentucky reference cigarette 2R4F (450 microg total particulate matter/l) or to fresh air (control), 5 days a week, twice for 1 h per day with a 30-minute fresh air exposure break for 30, 60, or 90 days. Endpoints for hypertrophy-associated changes were heart weight to body weight ratio, ventricular expression of hypertrophy-associated genes, ischemic tolerance, and inotropic responsiveness to isoprenaline in post-ischemic hearts.Smoke-exposed SHR showed a significant elevation in heart weight to body weight ratio, increased mRNA expression of atrial natriuretic factor (ANF), transforming growth factor (TGF)-beta(1), ornithine decarboxylase (ODC), and parathyroid hormone-related protein in both ventricles compared to controls. Hearts from smoke-exposed SHR showed a reduced recovery after 30 min global ischemia during the first 5 min of reperfusion and loss of inotropic stimulation after 30 min reperfusion. Smoke cessation was sufficient to reverse most of these alterations. WKY exposed to smoke did not develop similar changes.Our data indicate that several aspects of myocardial hypertrophy are accelerated by smoking." @default.
• W2084355267 created "2016-06-24" @default.
• W2084355267 creator A5043904242 @default.
• W2084355267 creator A5046233384 @default.
• W2084355267 creator A5051400789 @default.
• W2084355267 creator A5075571587 @default.
• W2084355267 creator A5075997716 @default.
• W2084355267 creator A5088724322 @default.
• W2084355267 date "2007-11-01" @default.
• W2084355267 modified "2023-09-23" @default.
• W2084355267 title "Smoking accelerates the progression of hypertension-induced myocardial hypertrophy to heart failure in spontaneously hypertensive rats☆" @default.
• W2084355267 cites W1982770740 @default.
• W2084355267 cites W1994930453 @default.
• W2084355267 cites W2003745437 @default.
• W2084355267 cites W2004522582 @default.
• W2084355267 cites W2015887765 @default.
• W2084355267 cites W2020814497 @default.
• W2084355267 cites W2036468118 @default.
• W2084355267 cites W2036506694 @default.
• W2084355267 cites W2037117453 @default.
• W2084355267 cites W2045913809 @default.
• W2084355267 cites W2050438985 @default.
• W2084355267 cites W2059829634 @default.
• W2084355267 cites W2076288014 @default.
• W2084355267 cites W2086811578 @default.
• W2084355267 cites W2087432765 @default.
• W2084355267 cites W2092772070 @default.
• W2084355267 cites W2101377455 @default.
• W2084355267 cites W2101601744 @default.
• W2084355267 cites W2105802609 @default.
• W2084355267 cites W2118180567 @default.
• W2084355267 cites W2128761672 @default.
• W2084355267 cites W2129439677 @default.
• W2084355267 cites W2130271956 @default.
• W2084355267 cites W2131842265 @default.
• W2084355267 cites W2334499091 @default.
• W2084355267 cites W2518574064 @default.
• W2084355267 cites W4199501 @default.
• W2084355267 doi "https://doi.org/10.1016/j.cardiores.2007.06.033" @default.
• W2084355267 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17658497" @default.
• W2084355267 hasPublicationYear "2007" @default.
• W2084355267 type Work @default.
• W2084355267 sameAs 2084355267 @default.
• W2084355267 citedByCount "26" @default.
• W2084355267 countsByYear W20843552672012 @default.
• W2084355267 countsByYear W20843552672013 @default.
• W2084355267 countsByYear W20843552672014 @default.
• W2084355267 countsByYear W20843552672015 @default.
• W2084355267 countsByYear W20843552672016 @default.
• W2084355267 countsByYear W20843552672017 @default.
• W2084355267 countsByYear W20843552672018 @default.
• W2084355267 countsByYear W20843552672019 @default.
• W2084355267 countsByYear W20843552672020 @default.
• W2084355267 countsByYear W20843552672021 @default.
• W2084355267 countsByYear W20843552672022 @default.
• W2084355267 countsByYear W20843552672023 @default.
• W2084355267 crossrefType "journal-article" @default.
• W2084355267 hasAuthorship W2084355267A5043904242 @default.
• W2084355267 hasAuthorship W2084355267A5046233384 @default.
• W2084355267 hasAuthorship W2084355267A5051400789 @default.
• W2084355267 hasAuthorship W2084355267A5075571587 @default.
• W2084355267 hasAuthorship W2084355267A5075997716 @default.
• W2084355267 hasAuthorship W2084355267A5088724322 @default.
• W2084355267 hasBestOaLocation W20843552671 @default.
• W2084355267 hasConcept C126322002 @default.
• W2084355267 hasConcept C134018914 @default.
• W2084355267 hasConcept C164705383 @default.
• W2084355267 hasConcept C167414201 @default.
• W2084355267 hasConcept C2776002628 @default.
• W2084355267 hasConcept C2778198053 @default.
• W2084355267 hasConcept C71924100 @default.
• W2084355267 hasConcept C84393581 @default.
• W2084355267 hasConceptScore W2084355267C126322002 @default.
• W2084355267 hasConceptScore W2084355267C134018914 @default.
• W2084355267 hasConceptScore W2084355267C164705383 @default.
• W2084355267 hasConceptScore W2084355267C167414201 @default.
• W2084355267 hasConceptScore W2084355267C2776002628 @default.
• W2084355267 hasConceptScore W2084355267C2778198053 @default.
• W2084355267 hasConceptScore W2084355267C71924100 @default.
• W2084355267 hasConceptScore W2084355267C84393581 @default.
• W2084355267 hasIssue "2" @default.
• W2084355267 hasLocation W20843552671 @default.
• W2084355267 hasLocation W20843552672 @default.
• W2084355267 hasOpenAccess W2084355267 @default.
• W2084355267 hasPrimaryLocation W20843552671 @default.
• W2084355267 hasRelatedWork W1981654342 @default.
• W2084355267 hasRelatedWork W1989311450 @default.
• W2084355267 hasRelatedWork W1993394218 @default.
• W2084355267 hasRelatedWork W2032397571 @default.
• W2084355267 hasRelatedWork W2074656274 @default.
• W2084355267 hasRelatedWork W2095147394 @default.
• W2084355267 hasRelatedWork W2149272589 @default.
• W2084355267 hasRelatedWork W2159629462 @default.
• W2084355267 hasRelatedWork W2408890477 @default.
• W2084355267 hasRelatedWork W4376643968 @default.
• W2084355267 hasVolume "76" @default.
• W2084355267 isParatext "false" @default.
• W2084355267 isRetracted "false" @default.

• next