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• W2084356288 startingPage "847" @default.
• W2084356288 abstract "The urgent need for better cancer treatments has stimulated interest in employing small-animal models to evaluate potential drug therapies. Robust mouse models of many human cancers have been generated using sophisticated technologies for engineering germ-line mutations. As we enter into an age of targeted therapeutics, these strains provide novel platforms for validating new anticancer drugs, assessing therapeutic index, identifying surrogate markers of tumor progression, and defining epigenetic and environmental influences on tumorigenesis." @default.
• W2084356288 created "2016-06-24" @default.
• W2084356288 creator A5001957878 @default.
• W2084356288 creator A5023734568 @default.
• W2084356288 creator A5065106421 @default.
• W2084356288 date "2006-03-23" @default.
• W2084356288 modified "2023-10-12" @default.
• W2084356288 title "Harnessing preclinical mouse models to inform human clinical cancer trials" @default.
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