Matches in SemOpenAlex for { <https://semopenalex.org/work/W2084366900> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2084366900 endingPage "166" @default.
- W2084366900 startingPage "166" @default.
- W2084366900 abstract "We read with interest the recent short report by Au et al (2007) on the efficacy of rituximab in post-transplantation thrombotic microangiopathy (TM). The regression of related symptoms in four out of five patients was quite suprising. As the authors stated, a relationship between ADAMTS13 levels and the presence of anti-ADAMTS13 was not evident in post-transplantation TM. Furthermore, Au et al (2007) found no change in ADAMTS13 and anti-ADAMTS13 after treatment with rituximab. The genesis of TM after transplant may be more related to endothelial damage rather than an antibody-mediated lowering of ADAMTS13 levels (Peyvandi et al, 2006). We wonder whether rituximab was really responsible for the regression of TM in this small cohort of patients, rather than possible alternative contributory factors, e.g. the replacement of ciclosporin with tacrolimus and the use of steroids, which can probably control graft-versus-host disease (a known risk factor for TM), in three out of four responding patients. Furthermore, patients received a median of 13 plasma exchanges (range 7–17), though it has been reported that, in this setting, a longer treatment is needed to obtain significant regression of TM (Zeigler et al, 1995). We think that the role of rituximab in the treatment of post-transplantation TM is at least questionable, and a stronger biological background is needed before advocating use of this expensive drug in these circumstances." @default.
- W2084366900 created "2016-06-24" @default.
- W2084366900 creator A5018098518 @default.
- W2084366900 creator A5021060422 @default.
- W2084366900 creator A5080298171 @default.
- W2084366900 creator A5082045927 @default.
- W2084366900 date "2007-10-01" @default.
- W2084366900 modified "2023-09-23" @default.
- W2084366900 title "Rituximab in thrombotic microangiopathy" @default.
- W2084366900 cites W2048009057 @default.
- W2084366900 cites W2080388518 @default.
- W2084366900 doi "https://doi.org/10.1111/j.1365-2141.2007.06767.x" @default.
- W2084366900 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17854324" @default.
- W2084366900 hasPublicationYear "2007" @default.
- W2084366900 type Work @default.
- W2084366900 sameAs 2084366900 @default.
- W2084366900 citedByCount "1" @default.
- W2084366900 countsByYear W20843669002012 @default.
- W2084366900 crossrefType "journal-article" @default.
- W2084366900 hasAuthorship W2084366900A5018098518 @default.
- W2084366900 hasAuthorship W2084366900A5021060422 @default.
- W2084366900 hasAuthorship W2084366900A5080298171 @default.
- W2084366900 hasAuthorship W2084366900A5082045927 @default.
- W2084366900 hasBestOaLocation W20843669001 @default.
- W2084366900 hasConcept C126322002 @default.
- W2084366900 hasConcept C141071460 @default.
- W2084366900 hasConcept C159654299 @default.
- W2084366900 hasConcept C203014093 @default.
- W2084366900 hasConcept C2777878052 @default.
- W2084366900 hasConcept C2778585876 @default.
- W2084366900 hasConcept C2779134260 @default.
- W2084366900 hasConcept C2780653079 @default.
- W2084366900 hasConcept C2780921031 @default.
- W2084366900 hasConcept C2909675724 @default.
- W2084366900 hasConcept C2911091166 @default.
- W2084366900 hasConcept C71924100 @default.
- W2084366900 hasConcept C72563966 @default.
- W2084366900 hasConcept C89560881 @default.
- W2084366900 hasConceptScore W2084366900C126322002 @default.
- W2084366900 hasConceptScore W2084366900C141071460 @default.
- W2084366900 hasConceptScore W2084366900C159654299 @default.
- W2084366900 hasConceptScore W2084366900C203014093 @default.
- W2084366900 hasConceptScore W2084366900C2777878052 @default.
- W2084366900 hasConceptScore W2084366900C2778585876 @default.
- W2084366900 hasConceptScore W2084366900C2779134260 @default.
- W2084366900 hasConceptScore W2084366900C2780653079 @default.
- W2084366900 hasConceptScore W2084366900C2780921031 @default.
- W2084366900 hasConceptScore W2084366900C2909675724 @default.
- W2084366900 hasConceptScore W2084366900C2911091166 @default.
- W2084366900 hasConceptScore W2084366900C71924100 @default.
- W2084366900 hasConceptScore W2084366900C72563966 @default.
- W2084366900 hasConceptScore W2084366900C89560881 @default.
- W2084366900 hasIssue "1" @default.
- W2084366900 hasLocation W20843669001 @default.
- W2084366900 hasLocation W20843669002 @default.
- W2084366900 hasOpenAccess W2084366900 @default.
- W2084366900 hasPrimaryLocation W20843669001 @default.
- W2084366900 hasRelatedWork W2084366900 @default.
- W2084366900 hasRelatedWork W2124400226 @default.
- W2084366900 hasRelatedWork W2946198964 @default.
- W2084366900 hasRelatedWork W3033753898 @default.
- W2084366900 hasRelatedWork W3037949192 @default.
- W2084366900 hasRelatedWork W3104949179 @default.
- W2084366900 hasRelatedWork W3159566231 @default.
- W2084366900 hasRelatedWork W4234875595 @default.
- W2084366900 hasRelatedWork W4285801222 @default.
- W2084366900 hasRelatedWork W2036500077 @default.
- W2084366900 hasVolume "139" @default.
- W2084366900 isParatext "false" @default.
- W2084366900 isRetracted "false" @default.
- W2084366900 magId "2084366900" @default.
- W2084366900 workType "article" @default.