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- W2084430414 abstract "Background: While anonymous oocyte donation (AOD) yields high pregnancy rates, some recipients fail to conceive with their initial AOD cycle but are successful with a different donor. Objective: We chose to analyze donors that failed to yield a pregnancy in a recipient who later proved fertile with a second donor. We compared the donor's failed AOD cycles to successful donation cycles to determine if cycle characteristics were predictive of outcome. Materials & Methods: IRB-approved retrospective analysis of AOD cycles of donors that failed to yield a pregnancy in a recipient compared to cycles of the same donors in other recipients yielding pregnancy. Results: Cycle outcome measures and embryo characteristics were analyzed for the two groups. Analysis of retrieval and transfer outcomes are found in Table 1 and 2, respectively. Conclusions: In our population, AOD donors who fail to yield a pregnancy in a recipient have fewer fertilized oocytes and poorer quality embryos as compared to their successful cycles. This occurs despite homogeneity of characteristics. A donor's failure to produce a pregnancy with one recipient is not necessarily indicative of prognosis with other recipients.Tabled 1Table 1.Retrieval OutcomesFailed Cycle (n = 6)Successful Cycle (n = 17)pE2-date of hCG∗1798 (412)2160 (899).60Oocytes Retrieved∗13.2 (4.6)15.8 (7.7).74Mature Oocytes∗10.5 (3.2)12.8 (6.2).67Oocytes Inseminated∗13.2 (4.6)13.2 (7.0).19Fertilized Oocytes∗6.3 (2.7)10.2 (4.4).05Stimulation Length (D)11.5 (0.5)11.5 (1.4).69∗Mean (SD) Open table in a new tab Tabled 1Table 2.Transfer OutcomesFailed Cycle (n = 12)Successful Cycle (n = 28)pEmbryos thawed∗3.0 (0.9)3.0 (0.9).91Embryos survived∗2.8 (0.6)2.9 (1.0).96Embryos transferred∗2.8 (0.6)2.6 (0.7).52Embryo grade∗1.1 (0.4)0.7 (0.4).02Cell #∗5.3 (1.0)5.3 (1.4)1.00∗Mean (SD) Open table in a new tab ∗Mean (SD) ∗Mean (SD)" @default.
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- W2084430414 date "2007-04-01" @default.
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- W2084430414 title "Frozen Anonymous Oocyte Donor Cycles: Predictors of Success" @default.
- W2084430414 doi "https://doi.org/10.1016/j.fertnstert.2007.01.200" @default.
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