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- W2084440390 abstract "SUMMARY Immunoglobulin G Fc receptors (IgG FcRs) induced by human cytomegalovirus (HCMV) were isolated from solubilized HCMV-infected cell extracts by IgG affinity chromatography and analysed by Western blotting using 125I-labelled human IgG and Fc. FcR species of M r 130K, 65K, 50K and 38K were found to mediate the binding of IgG. The 130K and 65K FcRs were also detected on HCMV virions. All four FcRs were reactive with a murine monoclonal antibody to herpes simplex virus glycoprotein E. Anti-HCMV antibodies markedly inhibited the binding of 125I-labelled human IgG Fc to the 130K and 50K species but inhibited to a lesser extent the binding to the 65K FcR." @default.
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- W2084440390 date "1989-04-01" @default.
- W2084440390 modified "2023-09-30" @default.
- W2084440390 title "Characterization of IgG Fc Receptors Induced by Human Cytomegalovirus" @default.
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- W2084440390 doi "https://doi.org/10.1099/0022-1317-70-4-893" @default.
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