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- W2084476023 abstract "Abstract A systematic study of the adsorption and association of the cancerostatic drug actinomycin-C 1 (ACT) at a hanging mercury drop electrode (HMDE) has been conducted using phase-sensitive a.c. voltammetry and cyclic voltammetry (CV). At all bulk concentrations, the adsorbed layer is transformed into a condensed film by the significant stacking forces acting between adjacent rings of the phenoxazone residues. The nucleation and growth mechanism is confirmed and the data are analysed using the Avrami equation. The adsorption parameters for the condensed film were evaluated at various pH values. In addition, the preparative electrochemical reduction of ACT was performed using the large-scale electrolysis and differential pulse polarography. The consequences for DNA interaction and membrane adsorption are discussed." @default.
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- W2084476023 date "1995-03-01" @default.
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- W2084476023 title "Voltammetry of adsorbed cancerostatic actinomycins" @default.
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- W2084476023 doi "https://doi.org/10.1016/0302-4598(95)01767-9" @default.
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