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• W2084508907 abstract "Environmental lighting regulates numerous circadian rhythms, including the cycle in pineal serotonin N-acetyltransferase activity. Brief exposure of rats to light can shift the phase of this enzyme's circadian rhythm. Light also rapidly reduces nocturnal enzyme activity. Intraventricular injections of carbachol, a cholinergic agonist, can mimic both of these effects. Light and carbachol presumably act on the suprachiasmatic nucleus of the hypothalamus. These experiments demonstrate the feasibility of using a neuropharmacologic approach to the mechanisms underlying mammalian circadian rhythms." @default.
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• W2084508907 date "1979-01-26" @default.
• W2084508907 modified "2023-09-23" @default.
• W2084508907 title "Intraventricular Carbachol Mimics the Effects of Light on the Circadian Rhythm in the Rat Pineal Gland" @default.
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• W2084508907 doi "https://doi.org/10.1126/science.32619" @default.
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