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- W2084577533 abstract "Following preliminary studies with detomidine hydrochloride in 10 young buffaloes (Bubalus bubalis), the effects of an intramuscular injection of 40 /ixg.kg−1 were studied in 6 healthy buffaloes of VA to 2 years of age, weighing between 85 and 140 kg. Arterial blood pressure, central venous pressure, heart rate, electrocardiogram, electroencephalogram, respiratory rate, arterial pH, arterial and venous blood gases and rectal temperature were monitored before, and for an hour after, intramuscular injection of detomidine. Marked ataxia and sternal recumbency occurred within 10 minutes of injection, and an apparent complete recovery occurred in about 90 minutes. The electroencephalograms never demonstrated the high-voltage-low-frequency wave forms normally associated with sedation, but the animals appeared well sedated. After injection there was marked decrease in heart rate which then tended to increase but it remained significantly (P < 0.05) below pre-injection values at 60 minutes. The mean arterial pressure increased initially, especially when electrocardiogram showed AV block, but after 15 minutes it had declined to below pre-injection values. These changes in the arterial blood pressure were, however, not statistically significant. Central venous pressure tended to increase during sedation but except at 30 minutes this increase was not statistically significant. Rectal temperature, arterial pH, arterial carbon dioxide tension, standard bicarbonate and cranial vena caval oxygen tension did not show any significant variation. Respiratory rate and arterial oxygen tension decreased significantly." @default.
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- W2084577533 date "1994-07-01" @default.
- W2084577533 modified "2023-09-25" @default.
- W2084577533 title "Effects of detomidine in young water buffalo" @default.
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- W2084577533 doi "https://doi.org/10.1111/j.1467-2995.1994.tb00480.x" @default.
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