Matches in SemOpenAlex for { <https://semopenalex.org/work/W2084611075> ?p ?o ?g. }
- W2084611075 endingPage "975" @default.
- W2084611075 startingPage "965" @default.
- W2084611075 abstract "The unresolved mechanism by which a single strand of DNA recognizes homology in duplex DNA is central to understanding genetic recombination and repair of double-strand breaks. Using stopped-flow fluorescence we monitored strand exchange catalyzed by E. coli RecA protein, measuring simultaneously the rate of exchange of A:T base pairs and the rates of formation and dissociation of the three-stranded intermediates called synaptic complexes. The rate of exchange of A:T base pairs was indistinguishable from the rate of formation of synaptic complexes, whereas the rate of displacement of a single strand from complexes was five to ten times slower. This physical evidence shows that a subset of bases exchanges at a rate that is fast enough to account for recognition of homology. Together, several studies suggest that a mechanism governed by the dynamic structure of DNA and catalyzed by diverse enzymes underlies both recognition of homology and initiation of strand exchange." @default.
- W2084611075 created "2016-06-24" @default.
- W2084611075 creator A5012702313 @default.
- W2084611075 creator A5039706498 @default.
- W2084611075 creator A5046641156 @default.
- W2084611075 creator A5048319542 @default.
- W2084611075 creator A5052344044 @default.
- W2084611075 date "2004-09-01" @default.
- W2084611075 modified "2023-10-11" @default.
- W2084611075 title "Exchange of DNA Base Pairs that Coincides with Recognition of Homology Promoted by E. coli RecA Protein" @default.
- W2084611075 cites W1511299884 @default.
- W2084611075 cites W1579716589 @default.
- W2084611075 cites W1603496007 @default.
- W2084611075 cites W1965513685 @default.
- W2084611075 cites W1969528530 @default.
- W2084611075 cites W1969896771 @default.
- W2084611075 cites W1973720058 @default.
- W2084611075 cites W1984231288 @default.
- W2084611075 cites W1986588909 @default.
- W2084611075 cites W1988221598 @default.
- W2084611075 cites W1990322191 @default.
- W2084611075 cites W2006268714 @default.
- W2084611075 cites W2007050205 @default.
- W2084611075 cites W2008138719 @default.
- W2084611075 cites W2012016974 @default.
- W2084611075 cites W2013337345 @default.
- W2084611075 cites W2014075636 @default.
- W2084611075 cites W2017993624 @default.
- W2084611075 cites W2021925377 @default.
- W2084611075 cites W2027802373 @default.
- W2084611075 cites W2029366557 @default.
- W2084611075 cites W2033551900 @default.
- W2084611075 cites W2034035353 @default.
- W2084611075 cites W2035520068 @default.
- W2084611075 cites W2039305322 @default.
- W2084611075 cites W2047543073 @default.
- W2084611075 cites W2050457090 @default.
- W2084611075 cites W2055645204 @default.
- W2084611075 cites W2056377405 @default.
- W2084611075 cites W2065405928 @default.
- W2084611075 cites W2065680649 @default.
- W2084611075 cites W2069476125 @default.
- W2084611075 cites W2073440834 @default.
- W2084611075 cites W2081397502 @default.
- W2084611075 cites W2091751711 @default.
- W2084611075 cites W2092032702 @default.
- W2084611075 cites W2095084342 @default.
- W2084611075 cites W2098588909 @default.
- W2084611075 cites W2104341102 @default.
- W2084611075 cites W2111865859 @default.
- W2084611075 cites W2122099590 @default.
- W2084611075 cites W2122549489 @default.
- W2084611075 cites W2125181285 @default.
- W2084611075 cites W2135995702 @default.
- W2084611075 cites W2138553495 @default.
- W2084611075 cites W2142822333 @default.
- W2084611075 cites W2149681483 @default.
- W2084611075 cites W2150531185 @default.
- W2084611075 cites W2153211353 @default.
- W2084611075 cites W2153374436 @default.
- W2084611075 doi "https://doi.org/10.1016/j.molcel.2004.08.017" @default.
- W2084611075 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15383285" @default.
- W2084611075 hasPublicationYear "2004" @default.
- W2084611075 type Work @default.
- W2084611075 sameAs 2084611075 @default.
- W2084611075 citedByCount "70" @default.
- W2084611075 countsByYear W20846110752012 @default.
- W2084611075 countsByYear W20846110752013 @default.
- W2084611075 countsByYear W20846110752014 @default.
- W2084611075 countsByYear W20846110752015 @default.
- W2084611075 countsByYear W20846110752016 @default.
- W2084611075 countsByYear W20846110752017 @default.
- W2084611075 countsByYear W20846110752018 @default.
- W2084611075 countsByYear W20846110752019 @default.
- W2084611075 countsByYear W20846110752020 @default.
- W2084611075 countsByYear W20846110752021 @default.
- W2084611075 countsByYear W20846110752022 @default.
- W2084611075 crossrefType "journal-article" @default.
- W2084611075 hasAuthorship W2084611075A5012702313 @default.
- W2084611075 hasAuthorship W2084611075A5039706498 @default.
- W2084611075 hasAuthorship W2084611075A5046641156 @default.
- W2084611075 hasAuthorship W2084611075A5048319542 @default.
- W2084611075 hasAuthorship W2084611075A5052344044 @default.
- W2084611075 hasBestOaLocation W20846110751 @default.
- W2084611075 hasConcept C102931765 @default.
- W2084611075 hasConcept C104317684 @default.
- W2084611075 hasConcept C12554922 @default.
- W2084611075 hasConcept C147789679 @default.
- W2084611075 hasConcept C153957851 @default.
- W2084611075 hasConcept C156695909 @default.
- W2084611075 hasConcept C165525559 @default.
- W2084611075 hasConcept C171288974 @default.
- W2084611075 hasConcept C185581394 @default.
- W2084611075 hasConcept C185592680 @default.
- W2084611075 hasConcept C198268994 @default.
- W2084611075 hasConcept C24586158 @default.
- W2084611075 hasConcept C515207424 @default.
- W2084611075 hasConcept C54355233 @default.