Matches in SemOpenAlex for { <https://semopenalex.org/work/W2084653246> ?p ?o ?g. }
- W2084653246 endingPage "3162" @default.
- W2084653246 startingPage "3153" @default.
- W2084653246 abstract "Extract from the cultured freshwater cf. Oscillatoria sp. UIC 10045 showed antiproliferative activity against HT-29 cell line. Bioassay-guided fractionation led to the isolation of two new cyclic lipopeptides, named trichormamides C (1) and D (2). The planar structures were determined by combined analyses of HRESIMS, Q-TOF ESIMS/MS, and 1D and 2D NMR spectra. The absolute configurations of the amino acid residues were assigned by advanced Marfey's analysis after partial and complete acid hydrolysis. Trichormamides C (1) is a cyclic undecapeptide and D (2) is a cyclic dodecapeptide, both containing a lipophilic β-aminodecanoic acid residue. Trichormamide C (1) displayed antiproliferative activities against HT-29 and MDA-MB-435 cancer cell lines with IC50 values of 1.7 and 1.0μM, respectively, as well as anti-Mycobacterium tuberculosis activity with MIC value of 23.8μg/mL (17.3μM). Trichormamide D (2) was found to be less potent against both HT-29 and MDA-MB-435 cancer cell lines with IC50 values of 11.5 and 11.7μM, respectively." @default.
- W2084653246 created "2016-06-24" @default.
- W2084653246 creator A5007731416 @default.
- W2084653246 creator A5010171355 @default.
- W2084653246 creator A5022301230 @default.
- W2084653246 creator A5041328061 @default.
- W2084653246 creator A5041642106 @default.
- W2084653246 creator A5046929579 @default.
- W2084653246 creator A5052465031 @default.
- W2084653246 creator A5055539764 @default.
- W2084653246 creator A5056857276 @default.
- W2084653246 creator A5069904190 @default.
- W2084653246 creator A5084587249 @default.
- W2084653246 date "2015-07-01" @default.
- W2084653246 modified "2023-09-24" @default.
- W2084653246 title "Trichormamides C and D, antiproliferative cyclic lipopeptides from the cultured freshwater cyanobacterium cf. Oscillatoria sp. UIC 10045" @default.
- W2084653246 cites W1539714773 @default.
- W2084653246 cites W1967869305 @default.
- W2084653246 cites W1980283966 @default.
- W2084653246 cites W1988957091 @default.
- W2084653246 cites W1989567581 @default.
- W2084653246 cites W1990470594 @default.
- W2084653246 cites W1991909703 @default.
- W2084653246 cites W1992431970 @default.
- W2084653246 cites W2009846905 @default.
- W2084653246 cites W2037843616 @default.
- W2084653246 cites W2042294503 @default.
- W2084653246 cites W2054110159 @default.
- W2084653246 cites W2056828739 @default.
- W2084653246 cites W2063566175 @default.
- W2084653246 cites W2077781738 @default.
- W2084653246 cites W2079416759 @default.
- W2084653246 cites W2105570105 @default.
- W2084653246 cites W2150610836 @default.
- W2084653246 cites W2174836714 @default.
- W2084653246 cites W2321383259 @default.
- W2084653246 cites W2327674166 @default.
- W2084653246 cites W2475350473 @default.
- W2084653246 cites W2949320061 @default.
- W2084653246 doi "https://doi.org/10.1016/j.bmc.2015.04.073" @default.
- W2084653246 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4469202" @default.
- W2084653246 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26001342" @default.
- W2084653246 hasPublicationYear "2015" @default.
- W2084653246 type Work @default.
- W2084653246 sameAs 2084653246 @default.
- W2084653246 citedByCount "21" @default.
- W2084653246 countsByYear W20846532462015 @default.
- W2084653246 countsByYear W20846532462017 @default.
- W2084653246 countsByYear W20846532462018 @default.
- W2084653246 countsByYear W20846532462019 @default.
- W2084653246 countsByYear W20846532462020 @default.
- W2084653246 countsByYear W20846532462021 @default.
- W2084653246 countsByYear W20846532462023 @default.
- W2084653246 crossrefType "journal-article" @default.
- W2084653246 hasAuthorship W2084653246A5007731416 @default.
- W2084653246 hasAuthorship W2084653246A5010171355 @default.
- W2084653246 hasAuthorship W2084653246A5022301230 @default.
- W2084653246 hasAuthorship W2084653246A5041328061 @default.
- W2084653246 hasAuthorship W2084653246A5041642106 @default.
- W2084653246 hasAuthorship W2084653246A5046929579 @default.
- W2084653246 hasAuthorship W2084653246A5052465031 @default.
- W2084653246 hasAuthorship W2084653246A5055539764 @default.
- W2084653246 hasAuthorship W2084653246A5056857276 @default.
- W2084653246 hasAuthorship W2084653246A5069904190 @default.
- W2084653246 hasAuthorship W2084653246A5084587249 @default.
- W2084653246 hasBestOaLocation W20846532462 @default.
- W2084653246 hasConcept C185592680 @default.
- W2084653246 hasConcept C19549132 @default.
- W2084653246 hasConcept C202751555 @default.
- W2084653246 hasConcept C2777752497 @default.
- W2084653246 hasConcept C2777970379 @default.
- W2084653246 hasConcept C2779281246 @default.
- W2084653246 hasConcept C2779669040 @default.
- W2084653246 hasConcept C43617362 @default.
- W2084653246 hasConcept C515207424 @default.
- W2084653246 hasConcept C523546767 @default.
- W2084653246 hasConcept C54355233 @default.
- W2084653246 hasConcept C55493867 @default.
- W2084653246 hasConcept C60984968 @default.
- W2084653246 hasConcept C71240020 @default.
- W2084653246 hasConcept C81885089 @default.
- W2084653246 hasConcept C86803240 @default.
- W2084653246 hasConcept C94412978 @default.
- W2084653246 hasConcept C97428945 @default.
- W2084653246 hasConceptScore W2084653246C185592680 @default.
- W2084653246 hasConceptScore W2084653246C19549132 @default.
- W2084653246 hasConceptScore W2084653246C202751555 @default.
- W2084653246 hasConceptScore W2084653246C2777752497 @default.
- W2084653246 hasConceptScore W2084653246C2777970379 @default.
- W2084653246 hasConceptScore W2084653246C2779281246 @default.
- W2084653246 hasConceptScore W2084653246C2779669040 @default.
- W2084653246 hasConceptScore W2084653246C43617362 @default.
- W2084653246 hasConceptScore W2084653246C515207424 @default.
- W2084653246 hasConceptScore W2084653246C523546767 @default.
- W2084653246 hasConceptScore W2084653246C54355233 @default.
- W2084653246 hasConceptScore W2084653246C55493867 @default.
- W2084653246 hasConceptScore W2084653246C60984968 @default.
- W2084653246 hasConceptScore W2084653246C71240020 @default.