Matches in SemOpenAlex for { <https://semopenalex.org/work/W2084668093> ?p ?o ?g. }
- W2084668093 endingPage "147" @default.
- W2084668093 startingPage "137" @default.
- W2084668093 abstract "Platelet-activating factor (PAF), a family of phospholipid autacoids with potent pro-inflammatory activities, is present in saliva. The current study has quantitated various species of PAF isolated from normal human mixed saliva. Choline-containing, sn-2 acetylated phospholipids with sn-1 ether- or ester-linked fatty alcohol/acid moieties (alkyl-PAF or acyl-PAF, respectively) were evaluated after direct derivatization with pentafluorobenzoic (PFB) anhydride. Individual species of PFB-derivatized PAF were separated by gas chromatography prior to mass spectral analysis; quantitative estimates of six different species of PAF in saliva were made by comparison to corresponding authentic, synthetic PAF standards. In each saliva sample, all six species of PAF were readily detected by this facile procedure. The predominant PAF was 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine or 16:0-alkyl-PAF (0.75 +/- 0.09 pmol/ml saliva; mean +/- S.E.; n = 5) which represented only 30.4 +/- 1.5% of the total PAF. Substantial amounts of 18:1- and 18:0-alkyl-PAF and 16:0-acyl-PAF were also identified (0.52 +/- 0.07, 0.35 +/- 0.06, and 0.35 +/- 0.02 pmol/ml saliva, respectively). In summary, mass spectrometric analysis of PAF after direct derivatization with PFB anhydride has revealed that at least six different species of PAF are present in normal human mixed saliva. This structural diversity may represent an important aspect of homeostasis in the healthy oral cavity." @default.
- W2084668093 created "2016-06-24" @default.
- W2084668093 creator A5005466573 @default.
- W2084668093 creator A5006699242 @default.
- W2084668093 creator A5014974894 @default.
- W2084668093 creator A5015280359 @default.
- W2084668093 creator A5033261373 @default.
- W2084668093 creator A5041491078 @default.
- W2084668093 creator A5083133515 @default.
- W2084668093 creator A5086648107 @default.
- W2084668093 date "1995-11-01" @default.
- W2084668093 modified "2023-09-26" @default.
- W2084668093 title "Molecular heterogeneity of PAF in normal human mixed saliva: quantitative mass spectral analysis after direct derivatization of PAF with pentafluorobenzoic anhydride" @default.
- W2084668093 cites W1513212892 @default.
- W2084668093 cites W1514833272 @default.
- W2084668093 cites W1533758013 @default.
- W2084668093 cites W1542584079 @default.
- W2084668093 cites W1545377491 @default.
- W2084668093 cites W1570619967 @default.
- W2084668093 cites W1582706242 @default.
- W2084668093 cites W1828157025 @default.
- W2084668093 cites W1847430044 @default.
- W2084668093 cites W1955272010 @default.
- W2084668093 cites W1968469729 @default.
- W2084668093 cites W1968490387 @default.
- W2084668093 cites W1989598480 @default.
- W2084668093 cites W1990649603 @default.
- W2084668093 cites W1993195340 @default.
- W2084668093 cites W1993677326 @default.
- W2084668093 cites W1994211148 @default.
- W2084668093 cites W1995151468 @default.
- W2084668093 cites W1996072942 @default.
- W2084668093 cites W1997199366 @default.
- W2084668093 cites W1998091234 @default.
- W2084668093 cites W2000755900 @default.
- W2084668093 cites W2001682079 @default.
- W2084668093 cites W2001931630 @default.
- W2084668093 cites W2004709228 @default.
- W2084668093 cites W2006104282 @default.
- W2084668093 cites W2012856347 @default.
- W2084668093 cites W2017338958 @default.
- W2084668093 cites W2017598713 @default.
- W2084668093 cites W2036194106 @default.
- W2084668093 cites W2040500741 @default.
- W2084668093 cites W2045705715 @default.
- W2084668093 cites W2050052239 @default.
- W2084668093 cites W2051747578 @default.
- W2084668093 cites W2054607466 @default.
- W2084668093 cites W2075144480 @default.
- W2084668093 cites W2093780666 @default.
- W2084668093 cites W2113434905 @default.
- W2084668093 cites W2118990153 @default.
- W2084668093 cites W2141541055 @default.
- W2084668093 cites W2144992982 @default.
- W2084668093 cites W2152311269 @default.
- W2084668093 cites W2155817194 @default.
- W2084668093 cites W2171514292 @default.
- W2084668093 cites W2185437926 @default.
- W2084668093 cites W2345306993 @default.
- W2084668093 cites W2394577104 @default.
- W2084668093 cites W973133833 @default.
- W2084668093 cites W2004720120 @default.
- W2084668093 doi "https://doi.org/10.1016/0005-2760(95)00127-x" @default.
- W2084668093 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7488633" @default.
- W2084668093 hasPublicationYear "1995" @default.
- W2084668093 type Work @default.
- W2084668093 sameAs 2084668093 @default.
- W2084668093 citedByCount "23" @default.
- W2084668093 countsByYear W20846680932012 @default.
- W2084668093 crossrefType "journal-article" @default.
- W2084668093 hasAuthorship W2084668093A5005466573 @default.
- W2084668093 hasAuthorship W2084668093A5006699242 @default.
- W2084668093 hasAuthorship W2084668093A5014974894 @default.
- W2084668093 hasAuthorship W2084668093A5015280359 @default.
- W2084668093 hasAuthorship W2084668093A5033261373 @default.
- W2084668093 hasAuthorship W2084668093A5041491078 @default.
- W2084668093 hasAuthorship W2084668093A5083133515 @default.
- W2084668093 hasAuthorship W2084668093A5086648107 @default.
- W2084668093 hasConcept C134018914 @default.
- W2084668093 hasConcept C162356407 @default.
- W2084668093 hasConcept C178790620 @default.
- W2084668093 hasConcept C185592680 @default.
- W2084668093 hasConcept C2776923573 @default.
- W2084668093 hasConcept C2778918659 @default.
- W2084668093 hasConcept C2779020240 @default.
- W2084668093 hasConcept C2780263894 @default.
- W2084668093 hasConcept C2780407432 @default.
- W2084668093 hasConcept C41625074 @default.
- W2084668093 hasConcept C43617362 @default.
- W2084668093 hasConcept C504460877 @default.
- W2084668093 hasConcept C55493867 @default.
- W2084668093 hasConcept C86803240 @default.
- W2084668093 hasConceptScore W2084668093C134018914 @default.
- W2084668093 hasConceptScore W2084668093C162356407 @default.
- W2084668093 hasConceptScore W2084668093C178790620 @default.
- W2084668093 hasConceptScore W2084668093C185592680 @default.
- W2084668093 hasConceptScore W2084668093C2776923573 @default.
- W2084668093 hasConceptScore W2084668093C2778918659 @default.