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- W2084725544 abstract "Digital microfluidics involves the manipulation of molecules and materials in discrete packages. This paper reviews our work using amphiphilic magnetic microparticles constructed from porous silicon. An individual porous particle can be used to carry a nanomole or smaller quantities of a reagent, and assemblies of the particles can encapsulate and transport microliter droplets of liquid containing inorganic, organic, or biological molecules. The tracking and identification of each particle can be accomplished with spectral labels that are encoded into the particles during their synthesis. When used to chaperone liquid droplets, the labels can identify the separate droplets prior to mixing and also the combined droplets after mixing. Magnetic iron oxide nanoparticles encapsulated in the porous matrix allow the manipulation of the particles or whole droplet assemblies with a magnetic field, and they also allow heating of the particle's payload by means of an externally applied RF field. Examples of organic, inorganic, and biomolecular addition reactions, catalytic reactions, and thermolysis reactions are described." @default.
- W2084725544 created "2016-06-24" @default.
- W2084725544 creator A5014215800 @default.
- W2084725544 creator A5059375688 @default.
- W2084725544 creator A5090541309 @default.
- W2084725544 date "2008-01-01" @default.
- W2084725544 modified "2023-10-01" @default.
- W2084725544 title "Digital microfluidics and delivery of molecular payloads with magnetic porous silicon chaperones" @default.
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- W2084725544 doi "https://doi.org/10.1039/b714594b" @default.
- W2084725544 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18239825" @default.
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