Matches in SemOpenAlex for { <https://semopenalex.org/work/W2084732011> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2084732011 endingPage "249" @default.
- W2084732011 startingPage "241" @default.
- W2084732011 abstract "An enzyme which acts on a synthetic collagenase substrate, 4-phenylazobenzyl-oxycarbonyl-l-Pro-l-Leu-Gly-l-Pro-d-Arg (Pz-peptide) has been purified 250-fold from soluble extracts of experimental granuloma tissue of the rat and its properties studied. It is optimally active around pH 7.2. Its apparent Km value for Pz-peptide is 0.01 mM and V is 100 nmoles/mg protein per min. It is reversibly inhibited by p-hydroxymercuribenzoate (PHMB) and HgCl2, whereas iodoacetamide does not affect the enzyme activity. Heavy metals like Cu2+, Cd2+, Ag+, Ni2+ and Zn2+ completely inhibit the enzyme activity while the inhibition by Co2+ was only partial. Fe2+, Ba2+, Mn2+, Pb2+ and Ca2+ did not exert any affect on the activity. Chelating agents like EDTA, sodium diethyl dithiocarbamate and α,α′-dipyridyl do not affect the enzyme activity. Approximate molecular weight of the purified enzyme was estimated to be 56 000." @default.
- W2084732011 created "2016-06-24" @default.
- W2084732011 creator A5018725788 @default.
- W2084732011 creator A5026263899 @default.
- W2084732011 date "1972-07-01" @default.
- W2084732011 modified "2023-09-23" @default.
- W2084732011 title "Purification and properties of a peptidase acting on a synthetic collagenase substrate from experimental granuloma tissue in the rat" @default.
- W2084732011 cites W1515225127 @default.
- W2084732011 cites W1750773183 @default.
- W2084732011 cites W1775749144 @default.
- W2084732011 cites W1994478019 @default.
- W2084732011 cites W1997026312 @default.
- W2084732011 cites W2006980225 @default.
- W2084732011 cites W2013561395 @default.
- W2084732011 cites W2087042766 @default.
- W2084732011 cites W217227600 @default.
- W2084732011 cites W2331064345 @default.
- W2084732011 cites W2411953877 @default.
- W2084732011 cites W2415737479 @default.
- W2084732011 doi "https://doi.org/10.1016/0005-2744(72)90026-5" @default.
- W2084732011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5047705" @default.
- W2084732011 hasPublicationYear "1972" @default.
- W2084732011 type Work @default.
- W2084732011 sameAs 2084732011 @default.
- W2084732011 citedByCount "22" @default.
- W2084732011 countsByYear W20847320112013 @default.
- W2084732011 crossrefType "journal-article" @default.
- W2084732011 hasAuthorship W2084732011A5018725788 @default.
- W2084732011 hasAuthorship W2084732011A5026263899 @default.
- W2084732011 hasConcept C181199279 @default.
- W2084732011 hasConcept C185592680 @default.
- W2084732011 hasConcept C18903297 @default.
- W2084732011 hasConcept C203014093 @default.
- W2084732011 hasConcept C2777289219 @default.
- W2084732011 hasConcept C2778394429 @default.
- W2084732011 hasConcept C2779851118 @default.
- W2084732011 hasConcept C2780140890 @default.
- W2084732011 hasConcept C2994592520 @default.
- W2084732011 hasConcept C55493867 @default.
- W2084732011 hasConcept C86803240 @default.
- W2084732011 hasConcept C95444343 @default.
- W2084732011 hasConceptScore W2084732011C181199279 @default.
- W2084732011 hasConceptScore W2084732011C185592680 @default.
- W2084732011 hasConceptScore W2084732011C18903297 @default.
- W2084732011 hasConceptScore W2084732011C203014093 @default.
- W2084732011 hasConceptScore W2084732011C2777289219 @default.
- W2084732011 hasConceptScore W2084732011C2778394429 @default.
- W2084732011 hasConceptScore W2084732011C2779851118 @default.
- W2084732011 hasConceptScore W2084732011C2780140890 @default.
- W2084732011 hasConceptScore W2084732011C2994592520 @default.
- W2084732011 hasConceptScore W2084732011C55493867 @default.
- W2084732011 hasConceptScore W2084732011C86803240 @default.
- W2084732011 hasConceptScore W2084732011C95444343 @default.
- W2084732011 hasIssue "1" @default.
- W2084732011 hasLocation W20847320111 @default.
- W2084732011 hasLocation W20847320112 @default.
- W2084732011 hasOpenAccess W2084732011 @default.
- W2084732011 hasPrimaryLocation W20847320111 @default.
- W2084732011 hasRelatedWork W157820598 @default.
- W2084732011 hasRelatedWork W1964142648 @default.
- W2084732011 hasRelatedWork W1966418295 @default.
- W2084732011 hasRelatedWork W2028802841 @default.
- W2084732011 hasRelatedWork W2049627339 @default.
- W2084732011 hasRelatedWork W2056414502 @default.
- W2084732011 hasRelatedWork W2084732011 @default.
- W2084732011 hasRelatedWork W2108638730 @default.
- W2084732011 hasRelatedWork W2401628796 @default.
- W2084732011 hasRelatedWork W2410475055 @default.
- W2084732011 hasVolume "276" @default.
- W2084732011 isParatext "false" @default.
- W2084732011 isRetracted "false" @default.
- W2084732011 magId "2084732011" @default.
- W2084732011 workType "article" @default.