FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2084797317> ?p ?o ?g. }

• W2084797317 endingPage "546" @default.
• W2084797317 startingPage "541" @default.
• W2084797317 abstract "Abstract Objective —To evaluate effects of a high dose of methylprednisolone sodium succinate (MPSS) on function of polymorphonuclear neutrophilic leukocytes (PMNs) in dogs. Animals —7 healthy male Beagles (body weight, 10.5 to 15 kg; age, 2 to 4 years). Procedures —All dogs were treated by IV administration of a high dose of MPSS (30 mg/kg). Additional doses of MPSS (15 mg/kg) were administered IV at 2 and 6 hours and then at 6-hour intervals until 48 hours after the initial dose. Blood samples were collected before and 1, 2, 4, 7, and 14 days after completion of the MPSS administrations and used for evaluation of PMN functions. Isolated PMNs were used for assessment of functions, such as adhesion, migration, phagocytosis, and oxidative burst. Results —On days 1, 2, and 4 after completion of MPSS administration, there was a decrease in PMN expression of adhesion markers such as CD11b and CD18. There was a decrease in the phagocytotic ability of PMNs on days 1, 2, and 7 after completion of MPSS administration, with a reduction in the oxidative burst of PMNs detected on day 7. No significant changes were identified for migration. All functional changes returned to their pretreatment values by 14 days after completion of MPSS treatment. Conclusions and Clinical Relevance —Treatment with a high dose of MPSS suppressed PMN functions in dogs. Analysis of these results suggested that treatment with a high dose of MPSS can suppress some of the major functions of PMNs for at least 7 days." @default.
• W2084797317 created "2016-06-24" @default.
• W2084797317 creator A5002499574 @default.
• W2084797317 creator A5008386495 @default.
• W2084797317 creator A5009389140 @default.
• W2084797317 creator A5027796132 @default.
• W2084797317 creator A5065523661 @default.
• W2084797317 creator A5067990152 @default.
• W2084797317 creator A5078658966 @default.
• W2084797317 creator A5090343584 @default.
• W2084797317 date "2010-05-01" @default.
• W2084797317 modified "2023-10-06" @default.
• W2084797317 title "Evaluation of the function of polymorphonuclear neutrophilic leukocytes in healthy dogs given a high dose of methylprednisolone sodium succinate" @default.
• W2084797317 cites W186752733 @default.
• W2084797317 cites W1965809927 @default.
• W2084797317 cites W1976466497 @default.
• W2084797317 cites W1984523402 @default.
• W2084797317 cites W1992325315 @default.
• W2084797317 cites W1996680631 @default.
• W2084797317 cites W1998045371 @default.
• W2084797317 cites W1998966032 @default.
• W2084797317 cites W2015416352 @default.
• W2084797317 cites W2019880793 @default.
• W2084797317 cites W2025658240 @default.
• W2084797317 cites W2028023612 @default.
• W2084797317 cites W2041418626 @default.
• W2084797317 cites W2073891485 @default.
• W2084797317 cites W2077194689 @default.
• W2084797317 cites W2078558875 @default.
• W2084797317 cites W2080090214 @default.
• W2084797317 cites W2085680930 @default.
• W2084797317 cites W2093763580 @default.
• W2084797317 cites W2095802382 @default.
• W2084797317 cites W2100115551 @default.
• W2084797317 cites W2121588037 @default.
• W2084797317 cites W2145357604 @default.
• W2084797317 cites W2152505433 @default.
• W2084797317 cites W2153450942 @default.
• W2084797317 cites W2184937068 @default.
• W2084797317 cites W288528320 @default.
• W2084797317 cites W73143864 @default.
• W2084797317 doi "https://doi.org/10.2460/ajvr.71.5.541" @default.
• W2084797317 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20433380" @default.
• W2084797317 hasPublicationYear "2010" @default.
• W2084797317 type Work @default.
• W2084797317 sameAs 2084797317 @default.
• W2084797317 citedByCount "3" @default.
• W2084797317 countsByYear W20847973172012 @default.
• W2084797317 countsByYear W20847973172014 @default.
• W2084797317 countsByYear W20847973172021 @default.
• W2084797317 crossrefType "journal-article" @default.
• W2084797317 hasAuthorship W2084797317A5002499574 @default.
• W2084797317 hasAuthorship W2084797317A5008386495 @default.
• W2084797317 hasAuthorship W2084797317A5009389140 @default.
• W2084797317 hasAuthorship W2084797317A5027796132 @default.
• W2084797317 hasAuthorship W2084797317A5065523661 @default.
• W2084797317 hasAuthorship W2084797317A5067990152 @default.
• W2084797317 hasAuthorship W2084797317A5078658966 @default.
• W2084797317 hasAuthorship W2084797317A5090343584 @default.
• W2084797317 hasBestOaLocation W20847973171 @default.
• W2084797317 hasConcept C126322002 @default.
• W2084797317 hasConcept C160448771 @default.
• W2084797317 hasConcept C171779818 @default.
• W2084797317 hasConcept C185592680 @default.
• W2084797317 hasConcept C203014093 @default.
• W2084797317 hasConcept C2777983669 @default.
• W2084797317 hasConcept C2780372218 @default.
• W2084797317 hasConcept C53122370 @default.
• W2084797317 hasConcept C553184892 @default.
• W2084797317 hasConcept C71924100 @default.
• W2084797317 hasConcept C98274493 @default.
• W2084797317 hasConcept C99971728 @default.
• W2084797317 hasConceptScore W2084797317C126322002 @default.
• W2084797317 hasConceptScore W2084797317C160448771 @default.
• W2084797317 hasConceptScore W2084797317C171779818 @default.
• W2084797317 hasConceptScore W2084797317C185592680 @default.
• W2084797317 hasConceptScore W2084797317C203014093 @default.
• W2084797317 hasConceptScore W2084797317C2777983669 @default.
• W2084797317 hasConceptScore W2084797317C2780372218 @default.
• W2084797317 hasConceptScore W2084797317C53122370 @default.
• W2084797317 hasConceptScore W2084797317C553184892 @default.
• W2084797317 hasConceptScore W2084797317C71924100 @default.
• W2084797317 hasConceptScore W2084797317C98274493 @default.
• W2084797317 hasConceptScore W2084797317C99971728 @default.
• W2084797317 hasIssue "5" @default.
• W2084797317 hasLocation W20847973171 @default.
• W2084797317 hasLocation W20847973172 @default.
• W2084797317 hasOpenAccess W2084797317 @default.
• W2084797317 hasPrimaryLocation W20847973171 @default.
• W2084797317 hasRelatedWork W1979806936 @default.
• W2084797317 hasRelatedWork W1998280863 @default.
• W2084797317 hasRelatedWork W2033537659 @default.
• W2084797317 hasRelatedWork W2053719510 @default.
• W2084797317 hasRelatedWork W2070999103 @default.
• W2084797317 hasRelatedWork W2073876661 @default.
• W2084797317 hasRelatedWork W2092859182 @default.
• W2084797317 hasRelatedWork W2348618204 @default.
• W2084797317 hasRelatedWork W3168616996 @default.

• next