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- W2084818908 abstract "In order to study the effect of 5'-modification of 2'-deoxynucleoside on its anti-HCV activity, several analogues were synthesized and evaluated. Among the analogues, a 5'-deoxy-5'-phenacylated analogue exhibited a good anti-HCV activity with an EC(50) of 15.1 microM. This compound is expected to operate via a type of mechanism that does not involve a generally known 5'-O-triphosphorylation process." @default.
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- W2084818908 date "2008-08-01" @default.
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- W2084818908 title "Synthesis and evaluation of 5′-modified 2′-deoxyadenosine analogues as anti-hepatitis C virus agents" @default.
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- W2084818908 doi "https://doi.org/10.1016/j.bmcl.2008.07.015" @default.
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