FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2084829467> ?p ?o ?g. }

• W2084829467 endingPage "689" @default.
• W2084829467 startingPage "682" @default.
• W2084829467 abstract "Estrogen receptor-negative breast cancers generally are highly malignant, resistant to chemotherapy and poorly prognostic. Here we demonstrate that estrogen receptor-negative human breast cancer cell lines highly express Fra-1, c-Fos and c-Jun, components of the transcription factor, activator protein-1 (AP-1). Retrospective observation of breast cancer tissues obtained by core needle biopsy before surgery from stages II and III patients demonstrates that Fra-1 expression is high in estrogen receptor-negative human breast cancers, and negatively correlated to paclitaxel sensitivity. Ascochlorin, which suppresses cellular AP-1 activity, selectively kills estrogen receptor-negative human and mouse breast cancer cell lines, and prolongs the survival time of mice implanted with an estrogen receptor-negative mammary carcinoma. These results suggest that chemotherapy targeting AP-1 activity is a potent strategy for estrogen receptor-negative human breast cancers." @default.
• W2084829467 created "2016-06-24" @default.
• W2084829467 creator A5021313736 @default.
• W2084829467 creator A5029795978 @default.
• W2084829467 creator A5035603011 @default.
• W2084829467 creator A5043272237 @default.
• W2084829467 creator A5047647448 @default.
• W2084829467 creator A5066681523 @default.
• W2084829467 creator A5066988309 @default.
• W2084829467 creator A5074949368 @default.
• W2084829467 date "2007-11-01" @default.
• W2084829467 modified "2023-10-17" @default.
• W2084829467 title "Aberrant Expression of Fra-1 in Estrogen Receptor-negative Breast Cancers and Suppression of their Propagation In Vivo by Ascochlorin, an Antibiotic that Inhibits Cellular Activator Protein-1 Activity" @default.
• W2084829467 cites W1562190372 @default.
• W2084829467 cites W1873117454 @default.
• W2084829467 cites W1911339081 @default.
• W2084829467 cites W1972932538 @default.
• W2084829467 cites W1982496758 @default.
• W2084829467 cites W1987948412 @default.
• W2084829467 cites W2008162574 @default.
• W2084829467 cites W2013535202 @default.
• W2084829467 cites W2022420894 @default.
• W2084829467 cites W2024425140 @default.
• W2084829467 cites W2032543236 @default.
• W2084829467 cites W2032829396 @default.
• W2084829467 cites W2036990242 @default.
• W2084829467 cites W2041807746 @default.
• W2084829467 cites W2050685477 @default.
• W2084829467 cites W2057702550 @default.
• W2084829467 cites W2057921652 @default.
• W2084829467 cites W2061085863 @default.
• W2084829467 cites W2062008354 @default.
• W2084829467 cites W2065775174 @default.
• W2084829467 cites W2088667932 @default.
• W2084829467 cites W2099282071 @default.
• W2084829467 cites W2099498093 @default.
• W2084829467 cites W2103128092 @default.
• W2084829467 cites W2109836298 @default.
• W2084829467 cites W2114918609 @default.
• W2084829467 cites W2116188263 @default.
• W2084829467 cites W2128934491 @default.
• W2084829467 cites W2131942337 @default.
• W2084829467 cites W2134406847 @default.
• W2084829467 cites W2145220191 @default.
• W2084829467 cites W2162609478 @default.
• W2084829467 cites W2209621509 @default.
• W2084829467 cites W2313434678 @default.
• W2084829467 cites W2322523258 @default.
• W2084829467 cites W2325011840 @default.
• W2084829467 cites W2335761521 @default.
• W2084829467 cites W4249539092 @default.
• W2084829467 doi "https://doi.org/10.1038/ja.2007.87" @default.
• W2084829467 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18057697" @default.
• W2084829467 hasPublicationYear "2007" @default.
• W2084829467 type Work @default.
• W2084829467 sameAs 2084829467 @default.
• W2084829467 citedByCount "18" @default.
• W2084829467 countsByYear W20848294672012 @default.
• W2084829467 countsByYear W20848294672013 @default.
• W2084829467 countsByYear W20848294672015 @default.
• W2084829467 countsByYear W20848294672016 @default.
• W2084829467 countsByYear W20848294672017 @default.
• W2084829467 countsByYear W20848294672020 @default.
• W2084829467 countsByYear W20848294672022 @default.
• W2084829467 crossrefType "journal-article" @default.
• W2084829467 hasAuthorship W2084829467A5021313736 @default.
• W2084829467 hasAuthorship W2084829467A5029795978 @default.
• W2084829467 hasAuthorship W2084829467A5035603011 @default.
• W2084829467 hasAuthorship W2084829467A5043272237 @default.
• W2084829467 hasAuthorship W2084829467A5047647448 @default.
• W2084829467 hasAuthorship W2084829467A5066681523 @default.
• W2084829467 hasAuthorship W2084829467A5066988309 @default.
• W2084829467 hasAuthorship W2084829467A5074949368 @default.
• W2084829467 hasBestOaLocation W20848294671 @default.
• W2084829467 hasConcept C121608353 @default.
• W2084829467 hasConcept C126322002 @default.
• W2084829467 hasConcept C134018914 @default.
• W2084829467 hasConcept C150903083 @default.
• W2084829467 hasConcept C207001950 @default.
• W2084829467 hasConcept C2777164284 @default.
• W2084829467 hasConcept C502942594 @default.
• W2084829467 hasConcept C530470458 @default.
• W2084829467 hasConcept C71924100 @default.
• W2084829467 hasConcept C84606932 @default.
• W2084829467 hasConcept C86803240 @default.
• W2084829467 hasConcept C96307122 @default.
• W2084829467 hasConcept C98717036 @default.
• W2084829467 hasConceptScore W2084829467C121608353 @default.
• W2084829467 hasConceptScore W2084829467C126322002 @default.
• W2084829467 hasConceptScore W2084829467C134018914 @default.
• W2084829467 hasConceptScore W2084829467C150903083 @default.
• W2084829467 hasConceptScore W2084829467C207001950 @default.
• W2084829467 hasConceptScore W2084829467C2777164284 @default.
• W2084829467 hasConceptScore W2084829467C502942594 @default.
• W2084829467 hasConceptScore W2084829467C530470458 @default.
• W2084829467 hasConceptScore W2084829467C71924100 @default.
• W2084829467 hasConceptScore W2084829467C84606932 @default.
• W2084829467 hasConceptScore W2084829467C86803240 @default.

• next