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- W2084837384 abstract "Objective: To examine whether the total volumes of cerebrospinal fluid (CSF), cerebral grey matter and white matter were correlated with the experience of environmental stress in daily life situations.Method: Twenty-seven patients with psychosis underwent magnetic resonance imaging scanning and a random time-sampling self-assessment technique (Experience Sampling Method) to determine subjective daily life stress experiences. Total cerebral tissue volumes were derived from an automated segmentation procedure.Results: CSF volume was positively associated with daily life event-related stress (β=0.016, P=0.002), while the association with total white matter was negative (β=−0.013, P=0.005). The effects were independent of each other and of total cerebral volume and other confounders. No large or significant association was found with grey matter volume.Conclusion: Subjective stress experience in daily life is associated with increased CSF and reduced white matter volumes in patients with psychosis, suggesting functional significance of these cerebral measures." @default.
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- W2084837384 date "2003-03-01" @default.
- W2084837384 modified "2023-10-14" @default.
- W2084837384 title "Cerebral tissue alterations and daily life stress experience in psychosis" @default.
- W2084837384 doi "https://doi.org/10.1016/s0920-9964(03)81131-3" @default.
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