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• W2084837430 abstract "You have accessJournal of UrologyStone Disease: New Technology/SWL, Ureteroscopic or Percutaneous Stone Removal1 Apr 20111938 RISK OF DIABETES MELLITUS AND HYPERTENSION AFTER EXTRACORPOREAL SHOCK WAVE (ESWL) THERAPY FOR URINARY STONE DISEASE Reza Mehrazin, Michael Aleman, Jamin Brahmbhatt, Evan Dunn, Anthony Patterson, Christopher Ledbetter, and Robert Wake Reza MehrazinReza Mehrazin Memphis, TN More articles by this author , Michael AlemanMichael Aleman Memphis, TN More articles by this author , Jamin BrahmbhattJamin Brahmbhatt Memphis, TN More articles by this author , Evan DunnEvan Dunn Memphis, TN More articles by this author , Anthony PattersonAnthony Patterson Memphis, TN More articles by this author , Christopher LedbetterChristopher Ledbetter Memphis, TN More articles by this author , and Robert WakeRobert Wake Memphis, TN More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2011.02.2119AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES We evaluated a consecutive series of ESWL patients at a single institution to determine the risk of developing de novo diabetes mellitus and hypertension after the procedure. We then compared patient characteristics between the groups that developed these outcomes and those who did not, to determine specific risk factors for their development. METHODS We retrospectively analyzed the demographic information of 761 consecutive patients treated with ESWL at our institution, including BMI, age, race, gender, laterality of stone burden, number of treatments, pre- and post-treatment renal function, and presence of preoperative and postoperative HTN and DM to determine whether there were statistically significant differences among those who did and did not develop HTN and DM. HTN and DM diagnoses were based on a computerized diagnosis list and/or the presence of medical therapy for the disease. The data were then analyzed by chi-square test and by logistic regression analysis. RESULTS Of the 761 patients, 150 and 419 patients had pre-existing DM or HTN, respectively. Of the remaining patients, 56 (9.2%) developed de novo DM, while 87 (25.1%) developed de novo HTN. Upon multivariate analysis, Caucasian race (p=0.035), BMI >30 (p<0.0001), and more than one treatment (p=0.035) were found to be associated with the development of DM. Moreover, on multivariate analysis, BMI > 30 (p=0.017), right sided treatment (P=0.008), and decreased GFR (p=0.041) were found to be significantly associated with de novo HTN after ESWL. The mean follow-up was 65.6 months. CONCLUSIONS In our experience, obesity, Caucasian race, and increased number of treatments were found to be risk factors for development of de novo DM after ESWL; and obesity, right-sided treatments, and decline in renal function after ESWL were found to be risk factors for development of de novo HTN. Obesity may be associated with the development of these diseases in general, and decreased GFR may represent a result of the disease rather than a predictor of its development. The findings that repeat treatments and right-sided treatments predispose patients to the development of DM and HTN, respectively, are intriguing and may potentially influence the choice of treatment modality. These warrant further prospective study to determine if a true causal relationship exists. © 2011 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 185Issue 4SApril 2011Page: e775 Advertisement Copyright & Permissions© 2011 by American Urological Association Education and Research, Inc.MetricsAuthor Information Reza Mehrazin Memphis, TN More articles by this author Michael Aleman Memphis, TN More articles by this author Jamin Brahmbhatt Memphis, TN More articles by this author Evan Dunn Memphis, TN More articles by this author Anthony Patterson Memphis, TN More articles by this author Christopher Ledbetter Memphis, TN More articles by this author Robert Wake Memphis, TN More articles by this author Expand All Advertisement Advertisement PDF DownloadLoading ..." @default.
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• W2084837430 title "1938 RISK OF DIABETES MELLITUS AND HYPERTENSION AFTER EXTRACORPOREAL SHOCK WAVE (ESWL) THERAPY FOR URINARY STONE DISEASE" @default.
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