FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2084887961> ?p ?o ?g. }

• W2084887961 endingPage "771" @default.
• W2084887961 startingPage "768" @default.
• W2084887961 abstract "Cryptochrome (CRY), a photoreceptor for the circadian clock in Drosophila, binds to the clock component TIM in a light-dependent fashion and blocks its function. In mammals, genetic evidence suggests a role for CRYs within the clock, distinct from hypothetical photoreceptor functions. Mammalian CRY1 and CRY2 are here shown to act as light-independent inhibitors of CLOCK-BMAL1, the activator driving Per1 transcription. CRY1 or CRY2 (or both) showed light-independent interactions with CLOCK and BMAL1, as well as with PER1, PER2, and TIM. Thus, mammalian CRYs act as light-independent components of the circadian clock and probably regulate Per1 transcriptional cycling by contacting both the activator and its feedback inhibitors." @default.
• W2084887961 created "2016-06-24" @default.
• W2084887961 creator A5021725208 @default.
• W2084887961 creator A5084952908 @default.
• W2084887961 creator A5090813306 @default.
• W2084887961 date "1999-10-22" @default.
• W2084887961 modified "2023-10-02" @default.
• W2084887961 title "Light-Independent Role of CRY1 and CRY2 in the Mammalian Circadian Clock" @default.
• W2084887961 cites W1629086938 @default.
• W2084887961 cites W1661083499 @default.
• W2084887961 cites W1744822607 @default.
• W2084887961 cites W1973788573 @default.
• W2084887961 cites W1979385177 @default.
• W2084887961 cites W1981529935 @default.
• W2084887961 cites W1989535139 @default.
• W2084887961 cites W1992494470 @default.
• W2084887961 cites W2006907150 @default.
• W2084887961 cites W2009132775 @default.
• W2084887961 cites W2021654192 @default.
• W2084887961 cites W2030063045 @default.
• W2084887961 cites W2045647450 @default.
• W2084887961 cites W2048466060 @default.
• W2084887961 cites W2054513544 @default.
• W2084887961 cites W2065793682 @default.
• W2084887961 cites W2069446043 @default.
• W2084887961 cites W2088348233 @default.
• W2084887961 cites W2091188307 @default.
• W2084887961 cites W2095299680 @default.
• W2084887961 cites W2113297137 @default.
• W2084887961 cites W2146656260 @default.
• W2084887961 cites W2151305846 @default.
• W2084887961 cites W2151468131 @default.
• W2084887961 cites W2153382373 @default.
• W2084887961 cites W2165129325 @default.
• W2084887961 cites W2175171485 @default.
• W2084887961 doi "https://doi.org/10.1126/science.286.5440.768" @default.
• W2084887961 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10531061" @default.
• W2084887961 hasPublicationYear "1999" @default.
• W2084887961 type Work @default.
• W2084887961 sameAs 2084887961 @default.
• W2084887961 citedByCount "563" @default.
• W2084887961 countsByYear W20848879612012 @default.
• W2084887961 countsByYear W20848879612013 @default.
• W2084887961 countsByYear W20848879612014 @default.
• W2084887961 countsByYear W20848879612015 @default.
• W2084887961 countsByYear W20848879612016 @default.
• W2084887961 countsByYear W20848879612017 @default.
• W2084887961 countsByYear W20848879612018 @default.
• W2084887961 countsByYear W20848879612019 @default.
• W2084887961 countsByYear W20848879612020 @default.
• W2084887961 countsByYear W20848879612021 @default.
• W2084887961 countsByYear W20848879612022 @default.
• W2084887961 countsByYear W20848879612023 @default.
• W2084887961 crossrefType "journal-article" @default.
• W2084887961 hasAuthorship W2084887961A5021725208 @default.
• W2084887961 hasAuthorship W2084887961A5084952908 @default.
• W2084887961 hasAuthorship W2084887961A5090813306 @default.
• W2084887961 hasConcept C104317684 @default.
• W2084887961 hasConcept C121446783 @default.
• W2084887961 hasConcept C125168821 @default.
• W2084887961 hasConcept C130679736 @default.
• W2084887961 hasConcept C144543706 @default.
• W2084887961 hasConcept C169760540 @default.
• W2084887961 hasConcept C184738001 @default.
• W2084887961 hasConcept C2779064383 @default.
• W2084887961 hasConcept C2780360009 @default.
• W2084887961 hasConcept C38606739 @default.
• W2084887961 hasConcept C54355233 @default.
• W2084887961 hasConcept C86339819 @default.
• W2084887961 hasConcept C86803240 @default.
• W2084887961 hasConcept C88045685 @default.
• W2084887961 hasConcept C95444343 @default.
• W2084887961 hasConceptScore W2084887961C104317684 @default.
• W2084887961 hasConceptScore W2084887961C121446783 @default.
• W2084887961 hasConceptScore W2084887961C125168821 @default.
• W2084887961 hasConceptScore W2084887961C130679736 @default.
• W2084887961 hasConceptScore W2084887961C144543706 @default.
• W2084887961 hasConceptScore W2084887961C169760540 @default.
• W2084887961 hasConceptScore W2084887961C184738001 @default.
• W2084887961 hasConceptScore W2084887961C2779064383 @default.
• W2084887961 hasConceptScore W2084887961C2780360009 @default.
• W2084887961 hasConceptScore W2084887961C38606739 @default.
• W2084887961 hasConceptScore W2084887961C54355233 @default.
• W2084887961 hasConceptScore W2084887961C86339819 @default.
• W2084887961 hasConceptScore W2084887961C86803240 @default.
• W2084887961 hasConceptScore W2084887961C88045685 @default.
• W2084887961 hasConceptScore W2084887961C95444343 @default.
• W2084887961 hasIssue "5440" @default.
• W2084887961 hasLocation W20848879611 @default.
• W2084887961 hasLocation W20848879612 @default.
• W2084887961 hasOpenAccess W2084887961 @default.
• W2084887961 hasPrimaryLocation W20848879611 @default.
• W2084887961 hasRelatedWork W103616653 @default.
• W2084887961 hasRelatedWork W1965201873 @default.
• W2084887961 hasRelatedWork W2002970901 @default.
• W2084887961 hasRelatedWork W2035324233 @default.
• W2084887961 hasRelatedWork W2071335236 @default.
• W2084887961 hasRelatedWork W2108257813 @default.

• next