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• W2084889787 abstract "Sites of A3 adenosine receptor gene expression have not been fully explored nor has this gene's promoter activity been confirmed in vivo. Transgenic mice were generated in which 2.3 kb upstream of the transcriptional start site of the mouse A3 adenosine receptor was coupled to a beta-galactosidase reporter gene. Selective transgene expression was detected in testis and brain as well as at other sites in which A3 adenosine receptor message has not been previously reported, including retinal ganglion cells and smooth muscle cells of the cerebrospinal vasculature. Our study suggests that this promoter may be useful in the selective targeting of gene expression to specific tissues." @default.
• W2084889787 created "2016-06-24" @default.
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• W2084889787 date "2002-11-20" @default.
• W2084889787 modified "2023-10-14" @default.
• W2084889787 title "Activity of the A3 adenosine receptor gene promoter in transgenic mice: characterization of previously unidentified sites of expression" @default.
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• W2084889787 doi "https://doi.org/10.1016/s0014-5793(02)03612-8" @default.
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