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- W2084928131 abstract "To study benzodiazepine receptor (BZR) density and functional deficits in occipital lobe epilepsy.A 39-year-old man who had simple partial visual seizures after neurosurgical transtentorial extirpation of a pinealoma was studied by EEG, magnetic resonance imaging (MRI), and positron emission tomography (PET) of [18F]2-fluoro-2-deoxy-D-glucose (FDG) at rest and during visual activation task and[11C]flumazenil (FMZ).Electroencephalographic recordings were nonspecific, and MRI did not reveal any morphologic anomaly in the occipital lobe. Flumazenil-PET demonstrated a small epileptogenic region in the right visual association cortex and FDG-PET showed hypometabolism in a corresponding location and thalamic diaschisis. Stimulation of occipital metabolism by a continuous visual recognition task improved significantly the contrast between the dysfunctional zone and its surround.As BZR deficits are restricted to a small region, widespread hypometabolism in networks involved in visual information processing indicates an extensive functional deactivation by the epileptogenic focus." @default.
- W2084928131 created "2016-06-24" @default.
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- W2084928131 date "1997-03-01" @default.
- W2084928131 modified "2023-10-18" @default.
- W2084928131 title "Widespread Functional Deficits in Perception-Related Networks Demonstrated by PET in a Case with Simple Visual Seizures" @default.
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- W2084928131 doi "https://doi.org/10.1111/j.1528-1157.1997.tb01130.x" @default.
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