FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2084976694> ?p ?o ?g. }

• W2084976694 endingPage "102" @default.
• W2084976694 startingPage "95" @default.
• W2084976694 abstract "In mammals, cumulus expansion due to increased synthesis of hyaluronan was suggested to correlate with modification of the gap junction between cumulus cells and the oocyte, leading to cumulus expansion. We examined whether lysophosphatidic acid, a lipid mediator detected in mammalian body fluids, stimulates significant production of hyaluronan and thus affects mouse cumulus expansion in vitro.Cumulus-oocyte complexes isolated from the gonadotropin-treated ovaries of B6C3F1 mice were exposed to lysophosphatidic acid in the presence and absence of 0.3 % fetal bovine serum for measurement of cumulus expansion and released hyaluronan, respectively.Exogenously added lysophosphatidic acid concentration-dependently stimulated production of hyaluronan in the cumulus cell-oocyte complex, and the stimulatory effect of lysophosphatidic acid on hyaluronan production was mediated through the signal pathways, including LPA receptor-Gi coupling, EGF receptor transactivation, and activations of phosphatidylinositol-specific phospholipase C, protein kinase C and mitogen-activated protein kinases. LPA increased mRNA expression of tumor necrosis α-induced protein 6, a hyaluronan-binding protein, and expansion of cumulus cell-oocyte complex.Lysophosphatidic acid in follicular fluids may participate in physiological cumulus expansion before ovulation by stimulating production of hyaluronan and proteins that enable the association of hyaluronan with cumulus cells and oocytes." @default.
• W2084976694 created "2016-06-24" @default.
• W2084976694 creator A5003418768 @default.
• W2084976694 creator A5044096310 @default.
• W2084976694 creator A5049318310 @default.
• W2084976694 creator A5057374544 @default.
• W2084976694 creator A5068896637 @default.
• W2084976694 creator A5091525772 @default.
• W2084976694 creator A5091693030 @default.
• W2084976694 date "2013-10-05" @default.
• W2084976694 modified "2023-10-01" @default.
• W2084976694 title "Lysophosphatidic acid stimulates hyaluronan production by mouse cumulus-oocyte complexes" @default.
• W2084976694 cites W1893337122 @default.
• W2084976694 cites W1939868901 @default.
• W2084976694 cites W1964902422 @default.
• W2084976694 cites W1981231686 @default.
• W2084976694 cites W1984231873 @default.
• W2084976694 cites W1984724070 @default.
• W2084976694 cites W1987945086 @default.
• W2084976694 cites W1993444917 @default.
• W2084976694 cites W1999887046 @default.
• W2084976694 cites W2003054818 @default.
• W2084976694 cites W2004352810 @default.
• W2084976694 cites W2005339021 @default.
• W2084976694 cites W2010305100 @default.
• W2084976694 cites W2019062818 @default.
• W2084976694 cites W2019893685 @default.
• W2084976694 cites W2030771022 @default.
• W2084976694 cites W2037669421 @default.
• W2084976694 cites W2059281025 @default.
• W2084976694 cites W2060918215 @default.
• W2084976694 cites W2062462448 @default.
• W2084976694 cites W2067932399 @default.
• W2084976694 cites W2069478525 @default.
• W2084976694 cites W2090894343 @default.
• W2084976694 cites W2098615703 @default.
• W2084976694 cites W2108309419 @default.
• W2084976694 cites W2112880248 @default.
• W2084976694 cites W2123488059 @default.
• W2084976694 cites W2132772646 @default.
• W2084976694 cites W2140265914 @default.
• W2084976694 cites W2143274441 @default.
• W2084976694 cites W2159623504 @default.
• W2084976694 cites W2164255754 @default.
• W2084976694 cites W2164374301 @default.
• W2084976694 cites W2171160774 @default.
• W2084976694 doi "https://doi.org/10.1007/s12522-013-0169-6" @default.
• W2084976694 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5892993" @default.
• W2084976694 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29662370" @default.
• W2084976694 hasPublicationYear "2013" @default.
• W2084976694 type Work @default.
• W2084976694 sameAs 2084976694 @default.
• W2084976694 citedByCount "8" @default.
• W2084976694 countsByYear W20849766942016 @default.
• W2084976694 countsByYear W20849766942018 @default.
• W2084976694 countsByYear W20849766942019 @default.
• W2084976694 countsByYear W20849766942020 @default.
• W2084976694 countsByYear W20849766942021 @default.
• W2084976694 countsByYear W20849766942023 @default.
• W2084976694 crossrefType "journal-article" @default.
• W2084976694 hasAuthorship W2084976694A5003418768 @default.
• W2084976694 hasAuthorship W2084976694A5044096310 @default.
• W2084976694 hasAuthorship W2084976694A5049318310 @default.
• W2084976694 hasAuthorship W2084976694A5057374544 @default.
• W2084976694 hasAuthorship W2084976694A5068896637 @default.
• W2084976694 hasAuthorship W2084976694A5091525772 @default.
• W2084976694 hasAuthorship W2084976694A5091693030 @default.
• W2084976694 hasBestOaLocation W20849766941 @default.
• W2084976694 hasConcept C105702510 @default.
• W2084976694 hasConcept C170493617 @default.
• W2084976694 hasConcept C180899940 @default.
• W2084976694 hasConcept C185592680 @default.
• W2084976694 hasConcept C196843134 @default.
• W2084976694 hasConcept C2776661833 @default.
• W2084976694 hasConcept C2776690073 @default.
• W2084976694 hasConcept C2777529286 @default.
• W2084976694 hasConcept C2778928357 @default.
• W2084976694 hasConcept C55493867 @default.
• W2084976694 hasConcept C86803240 @default.
• W2084976694 hasConcept C95444343 @default.
• W2084976694 hasConceptScore W2084976694C105702510 @default.
• W2084976694 hasConceptScore W2084976694C170493617 @default.
• W2084976694 hasConceptScore W2084976694C180899940 @default.
• W2084976694 hasConceptScore W2084976694C185592680 @default.
• W2084976694 hasConceptScore W2084976694C196843134 @default.
• W2084976694 hasConceptScore W2084976694C2776661833 @default.
• W2084976694 hasConceptScore W2084976694C2776690073 @default.
• W2084976694 hasConceptScore W2084976694C2777529286 @default.
• W2084976694 hasConceptScore W2084976694C2778928357 @default.
• W2084976694 hasConceptScore W2084976694C55493867 @default.
• W2084976694 hasConceptScore W2084976694C86803240 @default.
• W2084976694 hasConceptScore W2084976694C95444343 @default.
• W2084976694 hasIssue "2" @default.
• W2084976694 hasLocation W20849766941 @default.
• W2084976694 hasLocation W20849766942 @default.
• W2084976694 hasLocation W20849766943 @default.
• W2084976694 hasLocation W20849766944 @default.
• W2084976694 hasOpenAccess W2084976694 @default.

• next