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- W2085044202 abstract "A prodrug consisting of a β-D-glucuronic acid linked to a self-immolative spacer (a N-(ortho-hydroxyphenyl)-N-methylcarbamate) and a phenolic nitrogen mustard was synthesised. As this prodrug was easily cleaved by a β-glucuronidase enzyme and displayed low cytotoxicity, it must be considered as appropriate for an ADEPT approach." @default.
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- W2085044202 date "1997-04-01" @default.
- W2085044202 modified "2023-09-25" @default.
- W2085044202 title "Glucuronide prodrugs of hydroxy compounds for antibody directed enzyme prodrug therapy (ADEPT) : A phenol nitrogen mustard carbamate" @default.
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- W2085044202 doi "https://doi.org/10.1016/s0960-894x(97)00157-1" @default.
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