Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085049360> ?p ?o ?g. }
- W2085049360 endingPage "1026" @default.
- W2085049360 startingPage "1017" @default.
- W2085049360 abstract "Neurotrophins are known to be involved in experience-dependent plasticity of the visual cortex. Here, we have characterized in detail the effects of intraventricular nerve growth factor infusion in monocularly deprived rats by using immunostaining for the immediate-early gene product Zif268 as a marker of functional activity with cellular resolution. We have taken advantage of the rapid regulation of Zif268 by visual input to reveal the cortical units that are responsive to the deprived eye after a period of monocular deprivation. We found that responses to the deprived eye were significantly preserved in the cortex of monocularly deprived rats infused with nerve growth factor. The effects of nerve growth factor were greater for cortical cells located in deep layers and with more peripheral receptive fields. Results from Zif268 staining correlated very well with those obtained by single-cell recordings from the visual cortex. Our results demonstrate that exogenous nerve growth factor preserves the functional input from the deprived eye, enabling cortical neurons to activate immediate-early gene expression in response to stimulation of the deprived eye. Furthermore, we show that the intraventricular infusion of nerve growth factor differentially affects the ocular dominance of cells at various depths and eccentricities in the developing cortex." @default.
- W2085049360 created "2016-06-24" @default.
- W2085049360 creator A5016100084 @default.
- W2085049360 creator A5033851375 @default.
- W2085049360 creator A5043647281 @default.
- W2085049360 creator A5071021225 @default.
- W2085049360 date "1999-07-01" @default.
- W2085049360 modified "2023-10-07" @default.
- W2085049360 title "Expression of the transcription factor Zif268 in the visual cortex of monocularly deprived rats: effects of nerve growth factor" @default.
- W2085049360 cites W1842266333 @default.
- W2085049360 cites W1910443171 @default.
- W2085049360 cites W1963806203 @default.
- W2085049360 cites W1973918689 @default.
- W2085049360 cites W1974972283 @default.
- W2085049360 cites W1975626658 @default.
- W2085049360 cites W1976648408 @default.
- W2085049360 cites W1979735199 @default.
- W2085049360 cites W1979896676 @default.
- W2085049360 cites W1987964421 @default.
- W2085049360 cites W1989053030 @default.
- W2085049360 cites W2006977548 @default.
- W2085049360 cites W2009490317 @default.
- W2085049360 cites W2010653960 @default.
- W2085049360 cites W2010909249 @default.
- W2085049360 cites W2014370874 @default.
- W2085049360 cites W2014716170 @default.
- W2085049360 cites W2027162857 @default.
- W2085049360 cites W2030163298 @default.
- W2085049360 cites W2030615547 @default.
- W2085049360 cites W2032215155 @default.
- W2085049360 cites W2035251383 @default.
- W2085049360 cites W2036512556 @default.
- W2085049360 cites W2040361910 @default.
- W2085049360 cites W2041045292 @default.
- W2085049360 cites W2046049225 @default.
- W2085049360 cites W2046656280 @default.
- W2085049360 cites W2047160088 @default.
- W2085049360 cites W2048146702 @default.
- W2085049360 cites W2049376965 @default.
- W2085049360 cites W2050613356 @default.
- W2085049360 cites W2054595326 @default.
- W2085049360 cites W2054648475 @default.
- W2085049360 cites W2057685447 @default.
- W2085049360 cites W2061127610 @default.
- W2085049360 cites W2064688408 @default.
- W2085049360 cites W2066210317 @default.
- W2085049360 cites W2071148558 @default.
- W2085049360 cites W2072806245 @default.
- W2085049360 cites W2075029484 @default.
- W2085049360 cites W2078316783 @default.
- W2085049360 cites W2085631765 @default.
- W2085049360 cites W2087416422 @default.
- W2085049360 cites W2087497042 @default.
- W2085049360 cites W2098553579 @default.
- W2085049360 cites W2115736681 @default.
- W2085049360 cites W2116360511 @default.
- W2085049360 cites W2118357539 @default.
- W2085049360 cites W2139988160 @default.
- W2085049360 cites W2145620166 @default.
- W2085049360 cites W2148334422 @default.
- W2085049360 cites W2150471545 @default.
- W2085049360 cites W2155185539 @default.
- W2085049360 cites W4242411440 @default.
- W2085049360 cites W4296759731 @default.
- W2085049360 cites W88851328 @default.
- W2085049360 doi "https://doi.org/10.1016/s0306-4522(98)00682-4" @default.
- W2085049360 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10391479" @default.
- W2085049360 hasPublicationYear "1999" @default.
- W2085049360 type Work @default.
- W2085049360 sameAs 2085049360 @default.
- W2085049360 citedByCount "30" @default.
- W2085049360 countsByYear W20850493602012 @default.
- W2085049360 countsByYear W20850493602013 @default.
- W2085049360 countsByYear W20850493602014 @default.
- W2085049360 countsByYear W20850493602023 @default.
- W2085049360 crossrefType "journal-article" @default.
- W2085049360 hasAuthorship W2085049360A5016100084 @default.
- W2085049360 hasAuthorship W2085049360A5033851375 @default.
- W2085049360 hasAuthorship W2085049360A5043647281 @default.
- W2085049360 hasAuthorship W2085049360A5071021225 @default.
- W2085049360 hasConcept C104317684 @default.
- W2085049360 hasConcept C126322002 @default.
- W2085049360 hasConcept C150194340 @default.
- W2085049360 hasConcept C169760540 @default.
- W2085049360 hasConcept C170493617 @default.
- W2085049360 hasConcept C183836922 @default.
- W2085049360 hasConcept C24998067 @default.
- W2085049360 hasConcept C2777348757 @default.
- W2085049360 hasConcept C2778423431 @default.
- W2085049360 hasConcept C2779083617 @default.
- W2085049360 hasConcept C2779345533 @default.
- W2085049360 hasConcept C2779555244 @default.
- W2085049360 hasConcept C2781041448 @default.
- W2085049360 hasConcept C55493867 @default.
- W2085049360 hasConcept C6084040 @default.
- W2085049360 hasConcept C71924100 @default.
- W2085049360 hasConcept C86803240 @default.
- W2085049360 hasConcept C92020748 @default.