FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085067028> ?p ?o ?g. }

• W2085067028 endingPage "284" @default.
• W2085067028 startingPage "275" @default.
• W2085067028 abstract "The effects of solvent pH on spectral properties and fluorescence decay kinetics were investigated in order to characterize the microenvironment of meso-tetraphenylporphine tetrasulphonate (TPPS4) taken up by cells. Steady-state absorption and fluorescence spectra of TPPS4 in buffer solutions of different pH were used to identify a ring protonated species at pH less than or equal to 4. This dictation could also be distinguished from the unprotonated form by its altered fluorescence decay time (3.5 vs. 11.4 ns). In addition, time-resolved spectroscopy gave some evidence of a monocationic species existing at pH 6-9. This was concluded from the occurrence of another component with a decay time of 5 ns. Measurements of the spectral and kinetic properties of the fluorescence emission of single epithelial cells (RR1022) incubated with TPPS4 indicated that the sensitizer was mainly localized in a microenvironment with a pH of 5, a value which occurs intracellularly only within lysosomes. Cells kept in the dark exhibited the characteristic spectra of both the dication and the neutral form. The fluorescence decay showed two components with decay times of 2.6 ns and 10.6 ns. Irradiation of the cells changed the decay times to 4.6 ns and 13.4 ns and the dication fluorescence emission peak vanished, which is in accordance with the results obtained from buffer solutions at pH greater than or equal to 6. Therefore, we deduce that the photodynamic action leads to a rupture of the lysosomes and that the sensitizer is released into the surrounding cytoplasm." @default.
• W2085067028 created "2016-06-24" @default.
• W2085067028 creator A5022579720 @default.
• W2085067028 creator A5035651956 @default.
• W2085067028 creator A5037334921 @default.
• W2085067028 creator A5053107753 @default.
• W2085067028 creator A5088830106 @default.
• W2085067028 date "1992-02-01" @default.
• W2085067028 modified "2023-10-14" @default.
• W2085067028 title "Intracellular localization of meso-tetraphenylporphine tetrasulphonate probed by time-resolved and microscopic fluorescence spectroscopy" @default.
• W2085067028 cites W101943147 @default.
• W2085067028 cites W1964625357 @default.
• W2085067028 cites W1985982217 @default.
• W2085067028 cites W1986533239 @default.
• W2085067028 cites W1986541930 @default.
• W2085067028 cites W2025556184 @default.
• W2085067028 cites W2028224679 @default.
• W2085067028 cites W2031680921 @default.
• W2085067028 cites W2033873138 @default.
• W2085067028 cites W2044845580 @default.
• W2085067028 cites W2080470265 @default.
• W2085067028 cites W2094634766 @default.
• W2085067028 cites W2134602068 @default.
• W2085067028 cites W2138990320 @default.
• W2085067028 cites W2318391338 @default.
• W2085067028 cites W4233982701 @default.
• W2085067028 doi "https://doi.org/10.1016/1011-1344(92)85029-t" @default.
• W2085067028 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1635012" @default.
• W2085067028 hasPublicationYear "1992" @default.
• W2085067028 type Work @default.
• W2085067028 sameAs 2085067028 @default.
• W2085067028 citedByCount "59" @default.
• W2085067028 countsByYear W20850670282015 @default.
• W2085067028 countsByYear W20850670282017 @default.
• W2085067028 countsByYear W20850670282019 @default.
• W2085067028 countsByYear W20850670282020 @default.
• W2085067028 crossrefType "journal-article" @default.
• W2085067028 hasAuthorship W2085067028A5022579720 @default.
• W2085067028 hasAuthorship W2085067028A5035651956 @default.
• W2085067028 hasAuthorship W2085067028A5037334921 @default.
• W2085067028 hasAuthorship W2085067028A5053107753 @default.
• W2085067028 hasAuthorship W2085067028A5088830106 @default.
• W2085067028 hasConcept C113196181 @default.
• W2085067028 hasConcept C119824511 @default.
• W2085067028 hasConcept C120665830 @default.
• W2085067028 hasConcept C121332964 @default.
• W2085067028 hasConcept C125287762 @default.
• W2085067028 hasConcept C1276947 @default.
• W2085067028 hasConcept C133279788 @default.
• W2085067028 hasConcept C145148216 @default.
• W2085067028 hasConcept C148898269 @default.
• W2085067028 hasConcept C158711907 @default.
• W2085067028 hasConcept C159985019 @default.
• W2085067028 hasConcept C178790620 @default.
• W2085067028 hasConcept C185592680 @default.
• W2085067028 hasConcept C190062978 @default.
• W2085067028 hasConcept C192562407 @default.
• W2085067028 hasConcept C30095370 @default.
• W2085067028 hasConcept C32891209 @default.
• W2085067028 hasConcept C32909587 @default.
• W2085067028 hasConcept C43617362 @default.
• W2085067028 hasConcept C4839761 @default.
• W2085067028 hasConcept C55493867 @default.
• W2085067028 hasConcept C62520636 @default.
• W2085067028 hasConcept C66009135 @default.
• W2085067028 hasConcept C75473681 @default.
• W2085067028 hasConcept C91881484 @default.
• W2085067028 hasConcept C96141758 @default.
• W2085067028 hasConceptScore W2085067028C113196181 @default.
• W2085067028 hasConceptScore W2085067028C119824511 @default.
• W2085067028 hasConceptScore W2085067028C120665830 @default.
• W2085067028 hasConceptScore W2085067028C121332964 @default.
• W2085067028 hasConceptScore W2085067028C125287762 @default.
• W2085067028 hasConceptScore W2085067028C1276947 @default.
• W2085067028 hasConceptScore W2085067028C133279788 @default.
• W2085067028 hasConceptScore W2085067028C145148216 @default.
• W2085067028 hasConceptScore W2085067028C148898269 @default.
• W2085067028 hasConceptScore W2085067028C158711907 @default.
• W2085067028 hasConceptScore W2085067028C159985019 @default.
• W2085067028 hasConceptScore W2085067028C178790620 @default.
• W2085067028 hasConceptScore W2085067028C185592680 @default.
• W2085067028 hasConceptScore W2085067028C190062978 @default.
• W2085067028 hasConceptScore W2085067028C192562407 @default.
• W2085067028 hasConceptScore W2085067028C30095370 @default.
• W2085067028 hasConceptScore W2085067028C32891209 @default.
• W2085067028 hasConceptScore W2085067028C32909587 @default.
• W2085067028 hasConceptScore W2085067028C43617362 @default.
• W2085067028 hasConceptScore W2085067028C4839761 @default.
• W2085067028 hasConceptScore W2085067028C55493867 @default.
• W2085067028 hasConceptScore W2085067028C62520636 @default.
• W2085067028 hasConceptScore W2085067028C66009135 @default.
• W2085067028 hasConceptScore W2085067028C75473681 @default.
• W2085067028 hasConceptScore W2085067028C91881484 @default.
• W2085067028 hasConceptScore W2085067028C96141758 @default.
• W2085067028 hasIssue "3" @default.
• W2085067028 hasLocation W20850670281 @default.
• W2085067028 hasLocation W20850670282 @default.
• W2085067028 hasOpenAccess W2085067028 @default.

• next