FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085077030> ?p ?o ?g. }

• W2085077030 endingPage "470" @default.
• W2085077030 startingPage "464" @default.
• W2085077030 abstract "Five to 10% of patients with chronic myelogenous leukemia (CML) do not have the Philadelphia chromosome (Ph), but one-third of them have rearrangements of the breakpoint cluster region (BCR-positive).The authors analyzed the characteristics, treatment response, and prognosis of 23 patients with BCR-positive, Ph-negative CML, and compared them with patients with Ph-positive CML, Ph-negative BCR-negative CML and chronic myelomonocytic leukemia (CMML) treated during the same period.Seventeen patients had early chronic phase CML, 3 had late chronic phase, 2 had accelerated phase, and 1 had blastic phase. The median age was 44 years (range, 14-71 years), median platelet count was 402 x 10(9)/l, and median leukocyte count was 86 x 10(9)/l. Fourteen of the 17 patients with early chronic phase CML received alpha-interferon; 12 (86%) achieved complete hematologic remission. Median survival in chronic phase CML was 60 months (range, 3-90+ months). Patients with Ph-negative BCR-positive CML and those with Ph-positive CML had similar characteristics and outcome. Compared with patients with Ph-negative BCR-negative CML and CMML, patients with Ph-negative BCR-positive CML and Ph-positive CML were significantly younger, had a significantly higher incidence of leukocytosis, thrombocytosis, and peripheral and marrow basophilia, and a significantly lower incidence of anemia, thrombocytopenia, marrow blast percent, and peripheral and marrow monocytosis. The median survival was 60 months for Ph-negative BCR-positive CML, 73 months for Ph-positive CML, 25 months for Ph-negative BCR-negative CML, and 9 months for CMML (P < 0.001). When analyzed adjusting for their stage, patients classified with Ph-negative BCR-positive CML. Stage I disease had a significantly better survival than did patients with Ph-negative BCR-negative CML (P < 0.02).Patients with Ph-negative BCR-positive CML are similar to those with Ph-positive CML and should be treated with the same approaches." @default.
• W2085077030 created "2016-06-24" @default.
• W2085077030 creator A5006104041 @default.
• W2085077030 creator A5011529063 @default.
• W2085077030 creator A5015140142 @default.
• W2085077030 creator A5030171128 @default.
• W2085077030 creator A5057701424 @default.
• W2085077030 creator A5086948389 @default.
• W2085077030 creator A5090435894 @default.
• W2085077030 date "1995-01-15" @default.
• W2085077030 modified "2023-10-12" @default.
• W2085077030 title "Philadelphia chromosome-negative chronic myelogenous leukemia with rearrangement of the breakpoint cluster region. Long term follow-up results" @default.
• W2085077030 cites W1487237305 @default.
• W2085077030 cites W1976993340 @default.
• W2085077030 cites W1989333836 @default.
• W2085077030 cites W2019685656 @default.
• W2085077030 cites W2020252485 @default.
• W2085077030 cites W2056454565 @default.
• W2085077030 cites W2060833726 @default.
• W2085077030 cites W2063450941 @default.
• W2085077030 cites W2076372887 @default.
• W2085077030 cites W2089483984 @default.
• W2085077030 cites W2089697181 @default.
• W2085077030 cites W2224929038 @default.
• W2085077030 cites W2339475636 @default.
• W2085077030 cites W2410606477 @default.
• W2085077030 cites W34311289 @default.
• W2085077030 cites W4293241248 @default.
• W2085077030 doi "https://doi.org/10.1002/1097-0142(19950115)75:2<464::aid-cncr2820750209>3.0.co;2-e" @default.
• W2085077030 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7812917" @default.
• W2085077030 hasPublicationYear "1995" @default.
• W2085077030 type Work @default.
• W2085077030 sameAs 2085077030 @default.
• W2085077030 citedByCount "52" @default.
• W2085077030 countsByYear W20850770302012 @default.
• W2085077030 countsByYear W20850770302013 @default.
• W2085077030 countsByYear W20850770302015 @default.
• W2085077030 countsByYear W20850770302016 @default.
• W2085077030 countsByYear W20850770302017 @default.
• W2085077030 countsByYear W20850770302018 @default.
• W2085077030 countsByYear W20850770302020 @default.
• W2085077030 countsByYear W20850770302021 @default.
• W2085077030 countsByYear W20850770302022 @default.
• W2085077030 countsByYear W20850770302023 @default.
• W2085077030 crossrefType "journal-article" @default.
• W2085077030 hasAuthorship W2085077030A5006104041 @default.
• W2085077030 hasAuthorship W2085077030A5011529063 @default.
• W2085077030 hasAuthorship W2085077030A5015140142 @default.
• W2085077030 hasAuthorship W2085077030A5030171128 @default.
• W2085077030 hasAuthorship W2085077030A5057701424 @default.
• W2085077030 hasAuthorship W2085077030A5086948389 @default.
• W2085077030 hasAuthorship W2085077030A5090435894 @default.
• W2085077030 hasBestOaLocation W20850770301 @default.
• W2085077030 hasConcept C104317684 @default.
• W2085077030 hasConcept C126322002 @default.
• W2085077030 hasConcept C138626823 @default.
• W2085077030 hasConcept C170493617 @default.
• W2085077030 hasConcept C203014093 @default.
• W2085077030 hasConcept C2776960273 @default.
• W2085077030 hasConcept C2777583451 @default.
• W2085077030 hasConcept C2777928532 @default.
• W2085077030 hasConcept C2778461978 @default.
• W2085077030 hasConcept C2778729363 @default.
• W2085077030 hasConcept C2778904597 @default.
• W2085077030 hasConcept C2778923028 @default.
• W2085077030 hasConcept C2779788118 @default.
• W2085077030 hasConcept C2780007613 @default.
• W2085077030 hasConcept C2780506209 @default.
• W2085077030 hasConcept C2780817109 @default.
• W2085077030 hasConcept C2781087989 @default.
• W2085077030 hasConcept C3019892230 @default.
• W2085077030 hasConcept C43907098 @default.
• W2085077030 hasConcept C55493867 @default.
• W2085077030 hasConcept C71924100 @default.
• W2085077030 hasConcept C86803240 @default.
• W2085077030 hasConcept C89560881 @default.
• W2085077030 hasConcept C90924648 @default.
• W2085077030 hasConceptScore W2085077030C104317684 @default.
• W2085077030 hasConceptScore W2085077030C126322002 @default.
• W2085077030 hasConceptScore W2085077030C138626823 @default.
• W2085077030 hasConceptScore W2085077030C170493617 @default.
• W2085077030 hasConceptScore W2085077030C203014093 @default.
• W2085077030 hasConceptScore W2085077030C2776960273 @default.
• W2085077030 hasConceptScore W2085077030C2777583451 @default.
• W2085077030 hasConceptScore W2085077030C2777928532 @default.
• W2085077030 hasConceptScore W2085077030C2778461978 @default.
• W2085077030 hasConceptScore W2085077030C2778729363 @default.
• W2085077030 hasConceptScore W2085077030C2778904597 @default.
• W2085077030 hasConceptScore W2085077030C2778923028 @default.
• W2085077030 hasConceptScore W2085077030C2779788118 @default.
• W2085077030 hasConceptScore W2085077030C2780007613 @default.
• W2085077030 hasConceptScore W2085077030C2780506209 @default.
• W2085077030 hasConceptScore W2085077030C2780817109 @default.
• W2085077030 hasConceptScore W2085077030C2781087989 @default.
• W2085077030 hasConceptScore W2085077030C3019892230 @default.
• W2085077030 hasConceptScore W2085077030C43907098 @default.
• W2085077030 hasConceptScore W2085077030C55493867 @default.
• W2085077030 hasConceptScore W2085077030C71924100 @default.

• next