Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085078093> ?p ?o ?g. }
- W2085078093 endingPage "6" @default.
- W2085078093 startingPage "1" @default.
- W2085078093 abstract "For their growth, dormant tumors, which lack angiogenesis may critically depend on gradients of nutrients and oxygen from the nearest blood vessel. Because for oxygen depletion the distance from the nearest blood vessel to depletion will generally be shorter than for glucose depletion, such tumors will contain anoxic living tumor cells. These cells are dangerous, because they are capable of inducing angiogenesis, which will “wake up” the tumor. Anoxic cells are dependent on anaerobic glucose breakdown for ATP generation. The local extracellular glucose concentration gradient is determined by the blood glucose concentration and by consumption by cells closer to the nearest blood vessel. The blood glucose concentration can be lowered by 20–40% during fasting. We calculated that glucose supply to the potentially hazardous anoxic cells can thereby be reduced significantly, resulting in cell death specifically of the anoxic tumor cells. We hypothesize that intermittent fasting will help to reduce the incidence of tumor relapse via reducing the number of anoxic tumor cells and tumor awakening." @default.
- W2085078093 created "2016-06-24" @default.
- W2085078093 creator A5005845141 @default.
- W2085078093 creator A5043470360 @default.
- W2085078093 creator A5048187845 @default.
- W2085078093 creator A5062204088 @default.
- W2085078093 creator A5075677480 @default.
- W2085078093 creator A5082833455 @default.
- W2085078093 date "2015-01-01" @default.
- W2085078093 modified "2023-10-11" @default.
- W2085078093 title "A reason for intermittent fasting to suppress the awakening of dormant breast tumors" @default.
- W2085078093 cites W1758280303 @default.
- W2085078093 cites W1977335940 @default.
- W2085078093 cites W1978139448 @default.
- W2085078093 cites W1979679866 @default.
- W2085078093 cites W1979729004 @default.
- W2085078093 cites W1979973055 @default.
- W2085078093 cites W1990630374 @default.
- W2085078093 cites W1993497779 @default.
- W2085078093 cites W1995823607 @default.
- W2085078093 cites W1996447891 @default.
- W2085078093 cites W2003842905 @default.
- W2085078093 cites W2005895632 @default.
- W2085078093 cites W2006931309 @default.
- W2085078093 cites W2007394221 @default.
- W2085078093 cites W2008195780 @default.
- W2085078093 cites W2009240587 @default.
- W2085078093 cites W2010708650 @default.
- W2085078093 cites W2010969532 @default.
- W2085078093 cites W2020718934 @default.
- W2085078093 cites W2024843830 @default.
- W2085078093 cites W2028608252 @default.
- W2085078093 cites W2030892741 @default.
- W2085078093 cites W2035767445 @default.
- W2085078093 cites W2037236573 @default.
- W2085078093 cites W2055290232 @default.
- W2085078093 cites W2068838316 @default.
- W2085078093 cites W2072350925 @default.
- W2085078093 cites W2080264320 @default.
- W2085078093 cites W2091258584 @default.
- W2085078093 cites W2091975893 @default.
- W2085078093 cites W2092520171 @default.
- W2085078093 cites W2102416115 @default.
- W2085078093 cites W2102891340 @default.
- W2085078093 cites W2107940486 @default.
- W2085078093 cites W2109393326 @default.
- W2085078093 cites W2110421195 @default.
- W2085078093 cites W2121421529 @default.
- W2085078093 cites W2126099136 @default.
- W2085078093 cites W2128666917 @default.
- W2085078093 cites W2136417542 @default.
- W2085078093 cites W2136445803 @default.
- W2085078093 cites W2139271329 @default.
- W2085078093 cites W2140375832 @default.
- W2085078093 cites W2140575188 @default.
- W2085078093 cites W2145136453 @default.
- W2085078093 cites W2163578961 @default.
- W2085078093 cites W2327648646 @default.
- W2085078093 cites W4230026896 @default.
- W2085078093 cites W4250428608 @default.
- W2085078093 doi "https://doi.org/10.1016/j.biosystems.2014.11.001" @default.
- W2085078093 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25448890" @default.
- W2085078093 hasPublicationYear "2015" @default.
- W2085078093 type Work @default.
- W2085078093 sameAs 2085078093 @default.
- W2085078093 citedByCount "5" @default.
- W2085078093 countsByYear W20850780932016 @default.
- W2085078093 countsByYear W20850780932017 @default.
- W2085078093 countsByYear W20850780932019 @default.
- W2085078093 countsByYear W20850780932023 @default.
- W2085078093 crossrefType "journal-article" @default.
- W2085078093 hasAuthorship W2085078093A5005845141 @default.
- W2085078093 hasAuthorship W2085078093A5043470360 @default.
- W2085078093 hasAuthorship W2085078093A5048187845 @default.
- W2085078093 hasAuthorship W2085078093A5062204088 @default.
- W2085078093 hasAuthorship W2085078093A5075677480 @default.
- W2085078093 hasAuthorship W2085078093A5082833455 @default.
- W2085078093 hasConcept C108970007 @default.
- W2085078093 hasConcept C126322002 @default.
- W2085078093 hasConcept C134018914 @default.
- W2085078093 hasConcept C178790620 @default.
- W2085078093 hasConcept C185592680 @default.
- W2085078093 hasConcept C18903297 @default.
- W2085078093 hasConcept C2113261 @default.
- W2085078093 hasConcept C2780394083 @default.
- W2085078093 hasConcept C28406088 @default.
- W2085078093 hasConcept C502942594 @default.
- W2085078093 hasConcept C540031477 @default.
- W2085078093 hasConcept C71924100 @default.
- W2085078093 hasConcept C86803240 @default.
- W2085078093 hasConcept C95444343 @default.
- W2085078093 hasConceptScore W2085078093C108970007 @default.
- W2085078093 hasConceptScore W2085078093C126322002 @default.
- W2085078093 hasConceptScore W2085078093C134018914 @default.
- W2085078093 hasConceptScore W2085078093C178790620 @default.
- W2085078093 hasConceptScore W2085078093C185592680 @default.
- W2085078093 hasConceptScore W2085078093C18903297 @default.
- W2085078093 hasConceptScore W2085078093C2113261 @default.