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- W2085080118 abstract "Experiments were performed to determine the type of cells undergoing thymidine incorporation in 7-day autologous mixed lymphocyte reactions (AMLR). Peripheral blood mononuclear cells (PBM) were separated into B cells, T cells, B + Null cells and T + Null cell-enriched populations. Cells were cultured in various combinations. Monocytes were removed to determine their influence on AMLR. The main thymidine-incorporating cells in cultures were shown to be Null cells and to a lesser extent T cells. Monocytes were found to have a more pronounced suppressor effect on stimulation of T cells by non-T cell populations in younger individuals than in the elderly. Whether Null cells undergo a spontaneous blastogenesis in culture or are stimulated by T or B cells, could not be answered by the present investigation." @default.
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- W2085080118 date "1983-01-01" @default.
- W2085080118 modified "2023-09-27" @default.
- W2085080118 title "Autologous mixed lymphocyte reaction in man: Further characterization of responding cells" @default.
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- W2085080118 doi "https://doi.org/10.1016/0165-2478(83)90023-8" @default.
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