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• W2085081711 abstract "We have identified a protein that binds specifically to an origin of replication (oris) of the herpes simplex virus type 1 genome. The oris binding protein, detectable only in nuclear extracts of infected cells, shows the same time course of appearance as the herpesvirus-induced DNA polymerase and the DNA binding protein ICP8. The partially purified oris binding protein generates a DNase I footprint that spans 18- of the 90-base-pair minimal oris sequence. The oris binding protein may, therefore, be analogous to other origin-specific binding proteins that are required for the initiation of viral and chromosomal DNA replication." @default.
• W2085081711 created "2016-06-24" @default.
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• W2085081711 date "1986-09-01" @default.
• W2085081711 modified "2023-09-26" @default.
• W2085081711 title "A DNA binding protein specific for an origin of replication of herpes simplex virus type 1." @default.
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• W2085081711 doi "https://doi.org/10.1073/pnas.83.17.6322" @default.
• W2085081711 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/386495" @default.
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