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• W2085096008 abstract "<h2>Summary</h2><h3>Objective</h3> Gastric inflation (GI) is a significant issue when ventilation is performed on unprotected airways. <h3>Design</h3> Experimental analysis on the respiratory effects of hose extended bag-valve ventilation devices designed to reduce inspiratory pressure and flow. <h3>Setting</h3> Laboratory with lung/oesophageal sphincter simulator and pressure-flow-volume analyser. Lung compliance: 300ml/kPa, airway resistance: 0.5kPa/l/s. Lower oesophageal sphincter pressure (LOSP): 0.5kPa. <h3>Interventions</h3> Bag-valve ventilation of lung simulator. Twelve academic dental staff members used four devices: Ambu^® Mark III attached to either a reservoir bag (R) or a pressure relief valve (SV), SMART BAG^® (SB), and Easy Grip^® (EG) as control. <h3>Results</h3> After Bonferroni correction (<i>p</i>-level of significance 0.0083) for multiple comparisons, no evidence of difference between inspiratory tidal volumes (TVIN) administered by use of R (median 137ml) and SB (149ml) was found. Differences in TVIN were only detected between R and SV (188ml) (<i>p</i>=0.002). Only a trend towards TVIN differences between SB and R in comparison to EG (195ml) was found (<i>p</i>=0.009). Distributions of peak pressures differed when R (median 0.7kPa) and SV (1.0kPa) (<i>p</i>=0.006) or SB (0.7kPa) and SV (<i>p</i>=0.002) were compared. Peak inspiratory flow rates differed between EG (median 59l/min) and R (32l/min) as well as SB (42l/min) and between SB and SV (50l/min) (all with <i>p</i>=0.001). GI was lowest by use of R (median 103ml) compared to all other devices (EG: 518ml, SV: 394ml, SB: 271ml) (<i>p</i>=0.001). The areas under the pressure/flow over time curves were larger during SB compared to R ventilation. Mean airway pressures were significantly lower by use of R (0.1kPa) compared to SB (0.3kPa) (<i>p</i><0.008). <h3>Conclusion</h3> Lowering GI by pressure-flow reduction may result in lower TV depending on the device used. Lowest GI resulted from R ventilation. This may be explained by the specific pressure/time or flow/time patterns achieved by use of this device." @default.
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• W2085096008 date "2008-08-01" @default.
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• W2085096008 title "Comparison of different flow-reducing bag-valve ventilation devices regarding respiratory mechanics and gastric inflation in an unprotected airway model" @default.
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• W2085096008 doi "https://doi.org/10.1016/j.resuscitation.2008.02.022" @default.
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