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- W2085103438 abstract "Summary In this study, the localization and appearance of synaptophysin‐immunoreactive (IR) nerve cells and their relationships with the developing gastric layers were studied by immunocytochemistry and light microscopy in the embryonic rat stomach. The stomachs of Wistar rat embryos aged 13–21 days were used. The first neuronal bodies and their processes containing synaptophysin‐immunoreactivity were observed on embryonic day 13. In contrast, synaptophysin‐IR nerve terminals were first observed between mesenchymal cells on embryonic day 14. These results indicate that synaptophysin is expressed in growing neurits and neuronal cell bodies before these neurones have established synaptic connections. The occurrences of mesenchymal cell condensation near synaptophysin‐IR neuroblasts on embryonic day 15 reflect an active nerve element‐specific mesenchymal cell induction resulting in the morphogenesis of muscle cells. Similarly, the appearance of glandular structures after synaptophysin‐IR neuroblasts, on embryonic day 18, suggests that the epithelial differentiation may be closely related to the neuronal maturation as well as other factors. Finally, synaptophysin is functionally important in neuronal development and maturation, together with the establishment of neuroneuronal and neuromuscular contacts and in epithelial differentiation." @default.
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- W2085103438 date "2004-05-12" @default.
- W2085103438 modified "2023-10-17" @default.
- W2085103438 title "Immunocytochemical Detection of Synaptophysin in Enteric Neurones during Prenatal Development in the Rat Stomach" @default.
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- W2085103438 doi "https://doi.org/10.1111/j.1439-0264.2004.00509.x" @default.
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