FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085108323> ?p ?o ?g. }

• W2085108323 endingPage "42" @default.
• W2085108323 startingPage "35" @default.
• W2085108323 abstract "The rate of recovery of rat myocardial alpha 1-adrenoceptor density and responsiveness after in vivo block with phenoxybenzamine (1 mg/kg, i.p.) have been investigated by measuring [3H]prazosin binding, and noradrenaline-stimulated [3H]inositol phosphate production. Repopulation of alpha 1-adrenoceptors was monoexponential, with a t1/2 of 33 h; functional recovery was also monoexponential, with t1/2 of 28 h. Furthermore, our results clearly demonstrate the absence of a receptor reserve for alpha 1-adrenoceptors mediating noradrenaline-stimulated phosphoinositide breakdown in rat myocardial tissue. These observations indicate a close relationship between the density of [3H]prazosin binding sites and the ability of alpha 1-adrenoceptors to respond to noradrenaline. Moreover, based on competition curves for inhibition of specific [3H]prazosin by WB-4101 to rat myocardial membranes 48 h and 7 days after the administration of phenoxybenzamine, the results suggest that rat myocardial membranes contain both alpha 1-adrenoceptors subtypes, i.e., alpha 1A and alpha 1B, in an approximate ratio of 20:80, and this relative ratio does not seem to be altered during the recovery process." @default.
• W2085108323 created "2016-06-24" @default.
• W2085108323 creator A5012938091 @default.
• W2085108323 creator A5034613131 @default.
• W2085108323 creator A5067823373 @default.
• W2085108323 creator A5076431782 @default.
• W2085108323 date "1994-01-01" @default.
• W2085108323 modified "2023-10-05" @default.
• W2085108323 title "In vivo recovery of α1-adrenoceptors in rat myocardial tissue after alkylation with phenoxybenzamine" @default.
• W2085108323 cites W1497356015 @default.
• W2085108323 cites W1529383919 @default.
• W2085108323 cites W1529674136 @default.
• W2085108323 cites W1775749144 @default.
• W2085108323 cites W1966428196 @default.
• W2085108323 cites W1971284770 @default.
• W2085108323 cites W1971578051 @default.
• W2085108323 cites W1972913997 @default.
• W2085108323 cites W1985329175 @default.
• W2085108323 cites W1995531077 @default.
• W2085108323 cites W1996334384 @default.
• W2085108323 cites W1998001336 @default.
• W2085108323 cites W2000374180 @default.
• W2085108323 cites W2006367578 @default.
• W2085108323 cites W2014747325 @default.
• W2085108323 cites W2017187900 @default.
• W2085108323 cites W2020404323 @default.
• W2085108323 cites W2021547301 @default.
• W2085108323 cites W2038254161 @default.
• W2085108323 cites W2054221246 @default.
• W2085108323 cites W2074391638 @default.
• W2085108323 cites W2077768830 @default.
• W2085108323 cites W2078011767 @default.
• W2085108323 cites W2086864073 @default.
• W2085108323 cites W2087880462 @default.
• W2085108323 cites W2104559308 @default.
• W2085108323 cites W2138468749 @default.
• W2085108323 cites W2147563836 @default.
• W2085108323 cites W2159438452 @default.
• W2085108323 cites W2314316819 @default.
• W2085108323 doi "https://doi.org/10.1016/0922-4106(94)90206-2" @default.
• W2085108323 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8137881" @default.
• W2085108323 hasPublicationYear "1994" @default.
• W2085108323 type Work @default.
• W2085108323 sameAs 2085108323 @default.
• W2085108323 citedByCount "10" @default.
• W2085108323 countsByYear W20851083232016 @default.
• W2085108323 crossrefType "journal-article" @default.
• W2085108323 hasAuthorship W2085108323A5012938091 @default.
• W2085108323 hasAuthorship W2085108323A5034613131 @default.
• W2085108323 hasAuthorship W2085108323A5067823373 @default.
• W2085108323 hasAuthorship W2085108323A5076431782 @default.
• W2085108323 hasConcept C126322002 @default.
• W2085108323 hasConcept C134018914 @default.
• W2085108323 hasConcept C141071460 @default.
• W2085108323 hasConcept C150903083 @default.
• W2085108323 hasConcept C170493617 @default.
• W2085108323 hasConcept C185592680 @default.
• W2085108323 hasConcept C207001950 @default.
• W2085108323 hasConcept C2775944032 @default.
• W2085108323 hasConcept C2776885963 @default.
• W2085108323 hasConcept C2777427919 @default.
• W2085108323 hasConcept C2778618036 @default.
• W2085108323 hasConcept C2780648677 @default.
• W2085108323 hasConcept C2780668150 @default.
• W2085108323 hasConcept C49453240 @default.
• W2085108323 hasConcept C64943373 @default.
• W2085108323 hasConcept C71924100 @default.
• W2085108323 hasConcept C86803240 @default.
• W2085108323 hasConceptScore W2085108323C126322002 @default.
• W2085108323 hasConceptScore W2085108323C134018914 @default.
• W2085108323 hasConceptScore W2085108323C141071460 @default.
• W2085108323 hasConceptScore W2085108323C150903083 @default.
• W2085108323 hasConceptScore W2085108323C170493617 @default.
• W2085108323 hasConceptScore W2085108323C185592680 @default.
• W2085108323 hasConceptScore W2085108323C207001950 @default.
• W2085108323 hasConceptScore W2085108323C2775944032 @default.
• W2085108323 hasConceptScore W2085108323C2776885963 @default.
• W2085108323 hasConceptScore W2085108323C2777427919 @default.
• W2085108323 hasConceptScore W2085108323C2778618036 @default.
• W2085108323 hasConceptScore W2085108323C2780648677 @default.
• W2085108323 hasConceptScore W2085108323C2780668150 @default.
• W2085108323 hasConceptScore W2085108323C49453240 @default.
• W2085108323 hasConceptScore W2085108323C64943373 @default.
• W2085108323 hasConceptScore W2085108323C71924100 @default.
• W2085108323 hasConceptScore W2085108323C86803240 @default.
• W2085108323 hasIssue "1" @default.
• W2085108323 hasLocation W20851083231 @default.
• W2085108323 hasLocation W20851083232 @default.
• W2085108323 hasOpenAccess W2085108323 @default.
• W2085108323 hasPrimaryLocation W20851083231 @default.
• W2085108323 hasRelatedWork W2033472167 @default.
• W2085108323 hasRelatedWork W2034583712 @default.
• W2085108323 hasRelatedWork W2049265001 @default.
• W2085108323 hasRelatedWork W2051743364 @default.
• W2085108323 hasRelatedWork W2053180878 @default.
• W2085108323 hasRelatedWork W2063619316 @default.
• W2085108323 hasRelatedWork W2082001899 @default.
• W2085108323 hasRelatedWork W2091022983 @default.

• next