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- W2085122703 abstract "Background: Sentinel lymph node status is highly predictive of overall axillary lymph node involvement. Intraoperative assessment potentially enables completion of axillary dissection at the same setting. The most commonly used methods are frozen section histology and imprint cytology. Real-time reverse transcriptase polymerase chain reaction (RT-PCR) assays have been recently developed. Objectives: To obtain summary estimates of the diagnostic accuracy of intraoperative tests for the detection of metastases in lymph nodes of patients with breast cancer. Selection criteria: Cross-sectional studies assessing the diagnostic accuracy of at least one index test for the detection of metastases in lymph nodes of patients with breast cancer were selected. Index tests included frozen section, touch imprint cytology or RT-PCR with the One-Step Nucleic Acid Amplification (OSNA) technique (Sysmex) or GeneSearch™ Breast Lymph Node (BLN) Assay (Veridex, LCC). The reference standard was permanent section HE69(24 Suppl):Abstract nr 1005." @default.
- W2085122703 created "2016-06-24" @default.
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- W2085122703 date "2009-12-15" @default.
- W2085122703 modified "2023-09-30" @default.
- W2085122703 title "Intraoperative Determination of Axillary Node Metastasis: Meta-Analysis of Diagnostic Accuracy Assessment Studies for Frozen Section, Imprint Cytology and Molecular Assays." @default.
- W2085122703 doi "https://doi.org/10.1158/0008-5472.sabcs-09-1005" @default.
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