FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085125996> ?p ?o ?g. }

• W2085125996 endingPage "25" @default.
• W2085125996 startingPage "21" @default.
• W2085125996 abstract "Bax-interacting factor-1 (Bif-1) binds to Bax, which in turn activates this proapoptotic protein. In the absence of Bif-1, the ability to induce apoptosis through the intrinsic pathway is greatly reduced. Merkel cell carcinoma (MCC) classically shows an aggressive behavior and lack of response to chemotherapy, which remains unexplained. Previous studies have documented the presence of Bax in MCC, but Bif-1 expression has not been evaluated. Herein, the expression of Bif-1 and Bax in cutaneous MCC is examined.The immunohistochemical expression of Bif-1 and Bax protein was examined in nine cases of MCC. Both positive and negative controls were conducted. All the cases were reviewed by a single dermatopathologist.Bif-1 was detected in nine cases (100%), and Bax was expressed in six cases (66%). The percent positive cells for Bif-1 in MCC ranged from 85% to 98% positive (mean 93.9%). At the same time, decreased Bax expression was shown with 0-8% positive cells (mean 3.45%).The increased expression of Bif-1 in MCC is associated with low levels of Bax staining. These findings suggest that the upregulation of Bif-1 could in part be responsible for tumorigenesis in cutaneous MCC. As shown, Bax and Bif-1 expression are not exclusively antithetical; therefore, future studies evaluating the expression of both proteins should be conducted." @default.
• W2085125996 created "2016-06-24" @default.
• W2085125996 creator A5007346383 @default.
• W2085125996 creator A5011922181 @default.
• W2085125996 creator A5040301191 @default.
• W2085125996 creator A5050389821 @default.
• W2085125996 creator A5061602647 @default.
• W2085125996 creator A5088302638 @default.
• W2085125996 date "2009-01-01" @default.
• W2085125996 modified "2023-09-27" @default.
• W2085125996 title "Bif-1 and Bax expression in cutaneous Merkel cell carcinoma" @default.
• W2085125996 cites W1963945959 @default.
• W2085125996 cites W1969379547 @default.
• W2085125996 cites W1990614709 @default.
• W2085125996 cites W1995150044 @default.
• W2085125996 cites W2016377579 @default.
• W2085125996 cites W2017671645 @default.
• W2085125996 cites W2019993801 @default.
• W2085125996 cites W2020796092 @default.
• W2085125996 cites W2021425674 @default.
• W2085125996 cites W2036185104 @default.
• W2085125996 cites W2038877524 @default.
• W2085125996 cites W2049180642 @default.
• W2085125996 cites W2058949267 @default.
• W2085125996 cites W2100185604 @default.
• W2085125996 cites W2103457557 @default.
• W2085125996 cites W2109327605 @default.
• W2085125996 cites W2113999599 @default.
• W2085125996 cites W2123344131 @default.
• W2085125996 cites W2143067729 @default.
• W2085125996 cites W2152247516 @default.
• W2085125996 cites W2162378963 @default.
• W2085125996 cites W2165546509 @default.
• W2085125996 cites W2750896950 @default.
• W2085125996 doi "https://doi.org/10.1111/j.1600-0560.2007.00945.x" @default.
• W2085125996 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19125733" @default.
• W2085125996 hasPublicationYear "2009" @default.
• W2085125996 type Work @default.
• W2085125996 sameAs 2085125996 @default.
• W2085125996 citedByCount "6" @default.
• W2085125996 countsByYear W20851259962013 @default.
• W2085125996 countsByYear W20851259962016 @default.
• W2085125996 countsByYear W20851259962019 @default.
• W2085125996 countsByYear W20851259962020 @default.
• W2085125996 crossrefType "journal-article" @default.
• W2085125996 hasAuthorship W2085125996A5007346383 @default.
• W2085125996 hasAuthorship W2085125996A5011922181 @default.
• W2085125996 hasAuthorship W2085125996A5040301191 @default.
• W2085125996 hasAuthorship W2085125996A5050389821 @default.
• W2085125996 hasAuthorship W2085125996A5061602647 @default.
• W2085125996 hasAuthorship W2085125996A5088302638 @default.
• W2085125996 hasConcept C104317684 @default.
• W2085125996 hasConcept C121608353 @default.
• W2085125996 hasConcept C126322002 @default.
• W2085125996 hasConcept C127561419 @default.
• W2085125996 hasConcept C142724271 @default.
• W2085125996 hasConcept C190283241 @default.
• W2085125996 hasConcept C204232928 @default.
• W2085125996 hasConcept C2777546739 @default.
• W2085125996 hasConcept C2778342957 @default.
• W2085125996 hasConcept C2780291066 @default.
• W2085125996 hasConcept C2909544034 @default.
• W2085125996 hasConcept C502942594 @default.
• W2085125996 hasConcept C55493867 @default.
• W2085125996 hasConcept C555283112 @default.
• W2085125996 hasConcept C6856738 @default.
• W2085125996 hasConcept C71924100 @default.
• W2085125996 hasConcept C86803240 @default.
• W2085125996 hasConceptScore W2085125996C104317684 @default.
• W2085125996 hasConceptScore W2085125996C121608353 @default.
• W2085125996 hasConceptScore W2085125996C126322002 @default.
• W2085125996 hasConceptScore W2085125996C127561419 @default.
• W2085125996 hasConceptScore W2085125996C142724271 @default.
• W2085125996 hasConceptScore W2085125996C190283241 @default.
• W2085125996 hasConceptScore W2085125996C204232928 @default.
• W2085125996 hasConceptScore W2085125996C2777546739 @default.
• W2085125996 hasConceptScore W2085125996C2778342957 @default.
• W2085125996 hasConceptScore W2085125996C2780291066 @default.
• W2085125996 hasConceptScore W2085125996C2909544034 @default.
• W2085125996 hasConceptScore W2085125996C502942594 @default.
• W2085125996 hasConceptScore W2085125996C55493867 @default.
• W2085125996 hasConceptScore W2085125996C555283112 @default.
• W2085125996 hasConceptScore W2085125996C6856738 @default.
• W2085125996 hasConceptScore W2085125996C71924100 @default.
• W2085125996 hasConceptScore W2085125996C86803240 @default.
• W2085125996 hasIssue "1" @default.
• W2085125996 hasLocation W20851259961 @default.
• W2085125996 hasLocation W20851259962 @default.
• W2085125996 hasOpenAccess W2085125996 @default.
• W2085125996 hasPrimaryLocation W20851259961 @default.
• W2085125996 hasRelatedWork W2000087781 @default.
• W2085125996 hasRelatedWork W2038310867 @default.
• W2085125996 hasRelatedWork W2077001329 @default.
• W2085125996 hasRelatedWork W2085125996 @default.
• W2085125996 hasRelatedWork W2137140663 @default.
• W2085125996 hasRelatedWork W2167374655 @default.
• W2085125996 hasRelatedWork W2318475616 @default.
• W2085125996 hasRelatedWork W2469112183 @default.

• next