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- W2085143880 abstract "Objective: To elucidate the clinical features and prognosis of multiple primary cancers, in order to make improvement of diagnosis and treatment. Methods: A total of 506 patients with two primary cancers admitted from 1973 to 2004 were analyzed retrospectively. Results: These cases accounted for 0.9% of all the hospitalized cases in the same period among which 126 were males, with the ratio of male to female 1:3. The median age at the onset of the first disease was 48 y (ranged from 24 to 77). The interval between the two cancers was longer in patients under 50 y and in males, but without statistical significance. The onset age of the two primary cancers was mainly centered around 40 to 60 y, while 70% of the second cancer occurred within 80 m after the first cancer but half of them occurred within five years. The interval between the two cancers played crucial role in affecting the prognosis (P<0.005). Conclusion: Fewer lethal cancers are involved in either the primary or the secondary malignancies. The interval between the two primaries contributes most to the prognoses." @default.
- W2085143880 created "2016-06-24" @default.
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- W2085143880 date "2005-03-01" @default.
- W2085143880 modified "2023-10-18" @default.
- W2085143880 title "Metachronous second primary cancers: Clinical analyses of 506 cases in a single institution" @default.
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- W2085143880 doi "https://doi.org/10.1007/s11670-005-0012-7" @default.
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