FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085144422> ?p ?o ?g. }

• W2085144422 endingPage "372" @default.
• W2085144422 startingPage "364" @default.
• W2085144422 abstract "Clinical observations suggest that immune mechanisms affect etiology and course of recurrent cystitis. A primate infection model was used to show that primary bladder infection with a uropathogenic P-fimbriated strain (binding to globoside present in the bladder wall) protects against rechallenge with homologous as well as heterologous Escherichia coli strains for up to 5-6 mo. In contrast, mutant derivatives producing P-fimbriae either lacking the tip adhesin protein or carrying an adhesin for which no bladder receptor was present, were unable to induce protection, even though they generated bladder infections of similar duration as the wild type. Therefore, the protective effect mediated by the adhesin seemed to depend upon the presence of its cognate receptor. Since the wild strain also mediated protection against mutants that lacked the adhesin, our data suggest that the globoside-binding PapG adhesin acts as an adjuvant during infection to enhance a specific response against other bacterial antigens. In fact, the globoside-binding strain DS17, but not the mutant DS17-1, unable to bind to membrane-bound globoside, elicited a secretory IgA response to LPS in urine. These in vivo findings suggest that bacterial adhesin-ligand interactions may have signaling functions of importance for the immune response." @default.
• W2085144422 created "2016-06-24" @default.
• W2085144422 creator A5010330990 @default.
• W2085144422 creator A5015269037 @default.
• W2085144422 creator A5018912381 @default.
• W2085144422 creator A5025856384 @default.
• W2085144422 creator A5058725701 @default.
• W2085144422 creator A5064646921 @default.
• W2085144422 creator A5089043381 @default.
• W2085144422 date "1997-07-15" @default.
• W2085144422 modified "2023-10-10" @default.
• W2085144422 title "Induction of protective immunity after escherichia coli bladder infection in primates. Dependence of the globoside-specific P-fimbrial tip adhesin and its cognate receptor." @default.
• W2085144422 cites W1022571150 @default.
• W2085144422 cites W116820504 @default.
• W2085144422 cites W1604295453 @default.
• W2085144422 cites W1797970090 @default.
• W2085144422 cites W1951197670 @default.
• W2085144422 cites W1958230690 @default.
• W2085144422 cites W1963650584 @default.
• W2085144422 cites W1964096332 @default.
• W2085144422 cites W1965407722 @default.
• W2085144422 cites W1976843436 @default.
• W2085144422 cites W1990897573 @default.
• W2085144422 cites W1995563569 @default.
• W2085144422 cites W2006341402 @default.
• W2085144422 cites W2009160229 @default.
• W2085144422 cites W2010201541 @default.
• W2085144422 cites W2020326478 @default.
• W2085144422 cites W2026725826 @default.
• W2085144422 cites W2028631728 @default.
• W2085144422 cites W2031082075 @default.
• W2085144422 cites W2044476084 @default.
• W2085144422 cites W2045552068 @default.
• W2085144422 cites W2049980417 @default.
• W2085144422 cites W2054722926 @default.
• W2085144422 cites W2055307913 @default.
• W2085144422 cites W2086538363 @default.
• W2085144422 cites W2091627659 @default.
• W2085144422 cites W2109359144 @default.
• W2085144422 cites W211318903 @default.
• W2085144422 cites W2118646525 @default.
• W2085144422 cites W2140421321 @default.
• W2085144422 cites W2168526937 @default.
• W2085144422 cites W2284752426 @default.
• W2085144422 cites W231283592 @default.
• W2085144422 cites W2410210120 @default.
• W2085144422 cites W2438140162 @default.
• W2085144422 cites W2468692989 @default.
• W2085144422 cites W3152144931 @default.
• W2085144422 cites W2414656669 @default.
• W2085144422 doi "https://doi.org/10.1172/jci119542" @default.
• W2085144422 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/508199" @default.
• W2085144422 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9218513" @default.
• W2085144422 hasPublicationYear "1997" @default.
• W2085144422 type Work @default.
• W2085144422 sameAs 2085144422 @default.
• W2085144422 citedByCount "24" @default.
• W2085144422 countsByYear W20851444222012 @default.
• W2085144422 countsByYear W20851444222014 @default.
• W2085144422 countsByYear W20851444222015 @default.
• W2085144422 countsByYear W20851444222017 @default.
• W2085144422 countsByYear W20851444222021 @default.
• W2085144422 countsByYear W20851444222022 @default.
• W2085144422 crossrefType "journal-article" @default.
• W2085144422 hasAuthorship W2085144422A5010330990 @default.
• W2085144422 hasAuthorship W2085144422A5015269037 @default.
• W2085144422 hasAuthorship W2085144422A5018912381 @default.
• W2085144422 hasAuthorship W2085144422A5025856384 @default.
• W2085144422 hasAuthorship W2085144422A5058725701 @default.
• W2085144422 hasAuthorship W2085144422A5064646921 @default.
• W2085144422 hasAuthorship W2085144422A5089043381 @default.
• W2085144422 hasBestOaLocation W20851444221 @default.
• W2085144422 hasConcept C104317684 @default.
• W2085144422 hasConcept C143065580 @default.
• W2085144422 hasConcept C146587185 @default.
• W2085144422 hasConcept C147483822 @default.
• W2085144422 hasConcept C170493617 @default.
• W2085144422 hasConcept C179470777 @default.
• W2085144422 hasConcept C203014093 @default.
• W2085144422 hasConcept C2780115692 @default.
• W2085144422 hasConcept C39103817 @default.
• W2085144422 hasConcept C547475151 @default.
• W2085144422 hasConcept C55493867 @default.
• W2085144422 hasConcept C86803240 @default.
• W2085144422 hasConcept C8891405 @default.
• W2085144422 hasConcept C89423630 @default.
• W2085144422 hasConceptScore W2085144422C104317684 @default.
• W2085144422 hasConceptScore W2085144422C143065580 @default.
• W2085144422 hasConceptScore W2085144422C146587185 @default.
• W2085144422 hasConceptScore W2085144422C147483822 @default.
• W2085144422 hasConceptScore W2085144422C170493617 @default.
• W2085144422 hasConceptScore W2085144422C179470777 @default.
• W2085144422 hasConceptScore W2085144422C203014093 @default.
• W2085144422 hasConceptScore W2085144422C2780115692 @default.
• W2085144422 hasConceptScore W2085144422C39103817 @default.
• W2085144422 hasConceptScore W2085144422C547475151 @default.
• W2085144422 hasConceptScore W2085144422C55493867 @default.
• W2085144422 hasConceptScore W2085144422C86803240 @default.

• next