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- W2085160014 abstract "Abstract Objective The inhibitory effects of Radix Salviae Miltiorrhizae Extract-F (RSME-F) on ethanol-induced gastric mucosal injury and microvascular injury and its effects on lipid peroxidation in rats were investigated. Methods In the study, 160–200 g Wistar male rats were randomly divided into different groups, including the blank control, the control, and RSME-F. 24-hour fasting was arranged before experiment, though water was allowed. Saline, ethanol, and RSME-F (1mL/100g) were fed to the rats respectively. 0.5 hour later the rats were sacrificed. Gastric mucosal lesion, gastric mucosal microvascular injury, gastric activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activity, and content of gastric mucosal malondialdehyde (MDA) were measured. Results Compared with the control group, the RSME-F group showed a decrease in gastric mucosal lesion (2.53 ± 0.50 vs 7.57 ± 0.22, P Conclusion It is believed that RSME-F inhibited gastric mucosal lesion and microvascular injury induced by ethanol. In addition, it played a role in promoting the gastric mucosal SOD and GSH-Px activity and in reducing the content of gastric mucosal MDA." @default.
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- W2085160014 date "2008-06-01" @default.
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- W2085160014 title "Inhibitory Effects of Radix Salviae Miltiorrhizae Extract-F on Ethanol-Induced Gastric Mucosal Lesion and Gastric Mucosal Blood Vessels Impairment and Its Effects on Lipid Peroxidation in Rats" @default.
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- W2085160014 doi "https://doi.org/10.1016/s1876-3553(09)60016-8" @default.
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