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- W2085174684 abstract "Two-cell and four-cell preimplantation mouse embryos were cocultured in vitro with fibroblasts producing the recombinant retrovirus M-MuLV-neo. No wildtype helper virus was detected in these cultures. Of the embryos that survived the in vitro cultivation and the reimplantation into foster mothers, 2 of 15 that were tested contained the proviral genome. The provirus integrated as a single copy at a unique site. We estimate that approximately equal to 20% of the cells in each of the two transgenic fetuses contained the provirus." @default.
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- W2085174684 title "Introduction of genes into preimplantation mouse embryos by use of a defective recombinant retrovirus." @default.
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- W2085174684 doi "https://doi.org/10.1073/pnas.83.2.366" @default.
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