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• W2085191144 abstract "Pap smear, colposcopy, and biopsy results were collected from 1988–1993 at a group of family planning clinics. Positive predictive values and likelihood ratios were calculated for diagnosis of high-grade lesions based on age and Pap smear results. One thousand and forty-seven colposcopies were logged; 771 had a biopsy or endocervical curettage. Seventy-nine (10%) were high-grade lesions. If only human papillomavirus (HPV) was reported on the Pap smear, the likelihood of a high-grade biopsy was lowest (positive predictive value, 4.5%; likelihood ratio, 0.4). Women under age 25 were less likely to have high-grade biopsies (positive predictive value, 7.3%; likelihood ratio 0.7). Repeat Pap smears for atypical cells of undetermined significance (ASCUS) and low grade squamous intra-epithelial lesion (LGSIL) showing only HPV in women under age 30 would have reduced the immediate colposcopy rate by 60% and delayed diagnosis of 23% of high-grade lesions. Consideration of patient age and whether HPV is the only Pap smear finding may reduce referral for immediate colposcopy. Diagn. Cytopathol. 1997;17:321–325. © 1997 Wiley-Liss, Inc." @default.
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• W2085191144 date "1997-11-01" @default.
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• W2085191144 title "Detection of high-grade cervical dysplasia: Impact of age and Bethesda System terminology" @default.
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• W2085191144 doi "https://doi.org/10.1002/(sici)1097-0339(199711)17:5<321::aid-dc3>3.0.co;2-d" @default.
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