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• W2085192973 abstract "Measurement of spinal cord evoked potentials (SCEPs) is proposed as a means of predicting locomotion outcome in the rat spinal cord injury (SCI) model. Using 55 rats, three reproducible peak waves (waves I, II and III) were observed during stimulation at the C7 level with recording at the L1 epidural space. Hemisection at the T13 level showed three wave loss patterns: wave III loss only, loss of both wave II and III, and loss of all three waves. Defining an ideal SCI model as establishment of stable monoparesis or paraparesis, all animals in the wave II-III loss group showed favorable results. Histological data and electrophysiological properties allowed reasonable assumptions of wave origin: wave I from extrapyramidal tracts, wave II from the ventral corticospinal tract, and wave III from the dorsal corticospinal tract. Complete destruction of pyramidal tracts in both dorsal and ventral fibers was essential for long-term impairment of locomotion." @default.
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• W2085192973 date "2007-11-01" @default.
• W2085192973 modified "2023-09-25" @default.
• W2085192973 title "Simple measurement of spinal cord evoked potential: A valuable data source in the rat spinal cord injury model" @default.
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• W2085192973 doi "https://doi.org/10.1016/j.jocn.2006.10.007" @default.
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