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- W2085195514 abstract "To the Editor:— We appreciate the opportunity to comment on the article by Drs. Fontana, Holt, and Mainland in this issue. We question whether a conclusion as to the efficacy or lack of efficacy of injection therapy is warranted in view of the manner in which the study was carried out. In the course of three studies, 1-3 embracing six pollen-study seasons, we have encountered three particularly difficult obstacles to the assessment of this form of therapy. These are (1) the establishment of experimental control (well appreciated by the authors); (2) the selection of suitable patients, and (3) assessment of the patients' progress. Neither we nor the authors would be engaged in this difficult enterprise today, after some 50 years of experience with injection therapy, if this brought about striking relief in the great majority of patients who receive it. Thus, from the start, one may anticipate difficulty in demonstrating" @default.
- W2085195514 created "2016-06-24" @default.
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- W2085195514 date "1966-03-21" @default.
- W2085195514 modified "2023-09-25" @default.
- W2085195514 title "Hyposensitization Therapy In Ragweed Hay Fever" @default.
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- W2085195514 doi "https://doi.org/10.1001/jama.1966.03100120139049" @default.
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