Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085202354> ?p ?o ?g. }
- W2085202354 endingPage "111" @default.
- W2085202354 startingPage "96" @default.
- W2085202354 abstract "A method for freeze-drying red blood cells (RBCs) while maintaining high viability has important implications in blood transfusion and clinical medicine. RBCs loaded with the disaccharide trehalose can be freeze-dried in a formulation of hydroxyethyl starch, human serum albumin, and trehalose to residual water contents between 2% and 4%. Rehydration of the freeze-dried erythrocytes resulted in about 55% survival, based on the percent hemolysis. The surviving cells can synthesize ATP and 2,3-DPG, have preserved morphology, and have low levels of methemoglobin. Biochemical analyses showed that the activities of superoxide dismutase and catalase in freezedried RBCs are very similar to those of fresh RBCs. Secondary structure of hemoglobin was similar to that of fresh hemoglobin. Trehalose loading is required to achieve the stabilization of hemoglobin. These data provide an important step towards a stable erythrocyte product, which can prove invaluable for transfusion and clinical applications." @default.
- W2085202354 created "2016-06-24" @default.
- W2085202354 creator A5013536350 @default.
- W2085202354 creator A5017836479 @default.
- W2085202354 creator A5020699066 @default.
- W2085202354 creator A5025900332 @default.
- W2085202354 creator A5043336909 @default.
- W2085202354 creator A5055488463 @default.
- W2085202354 creator A5071902523 @default.
- W2085202354 creator A5073724423 @default.
- W2085202354 creator A5074869230 @default.
- W2085202354 creator A5080908711 @default.
- W2085202354 creator A5082271642 @default.
- W2085202354 creator A5088816728 @default.
- W2085202354 date "2005-06-01" @default.
- W2085202354 modified "2023-09-26" @default.
- W2085202354 title "Preservation of Trehalose-Loaded Red Blood Cells by Lyophilization" @default.
- W2085202354 cites W1887679324 @default.
- W2085202354 cites W1971048984 @default.
- W2085202354 cites W1975049067 @default.
- W2085202354 cites W1981348164 @default.
- W2085202354 cites W1982530428 @default.
- W2085202354 cites W1983233459 @default.
- W2085202354 cites W1989345028 @default.
- W2085202354 cites W1992499929 @default.
- W2085202354 cites W1997731166 @default.
- W2085202354 cites W2008672969 @default.
- W2085202354 cites W2009665244 @default.
- W2085202354 cites W2012299674 @default.
- W2085202354 cites W2013429774 @default.
- W2085202354 cites W2019941436 @default.
- W2085202354 cites W2020495772 @default.
- W2085202354 cites W2020700452 @default.
- W2085202354 cites W2022513837 @default.
- W2085202354 cites W2024683216 @default.
- W2085202354 cites W2033778280 @default.
- W2085202354 cites W2041506075 @default.
- W2085202354 cites W2044378655 @default.
- W2085202354 cites W2046331902 @default.
- W2085202354 cites W2050424694 @default.
- W2085202354 cites W2052664734 @default.
- W2085202354 cites W2053025857 @default.
- W2085202354 cites W2060823909 @default.
- W2085202354 cites W2062102053 @default.
- W2085202354 cites W2062300003 @default.
- W2085202354 cites W2063896494 @default.
- W2085202354 cites W2065442539 @default.
- W2085202354 cites W2066290712 @default.
- W2085202354 cites W2075050043 @default.
- W2085202354 cites W2077231187 @default.
- W2085202354 cites W2088107416 @default.
- W2085202354 cites W2091484714 @default.
- W2085202354 cites W2121936687 @default.
- W2085202354 cites W2129887903 @default.
- W2085202354 cites W2151991230 @default.
- W2085202354 cites W2157544220 @default.
- W2085202354 cites W2159426997 @default.
- W2085202354 cites W2168526937 @default.
- W2085202354 cites W2287615193 @default.
- W2085202354 cites W2407228341 @default.
- W2085202354 cites W93254315 @default.
- W2085202354 cites W994527693 @default.
- W2085202354 doi "https://doi.org/10.1089/cpt.2005.3.96" @default.
- W2085202354 hasPublicationYear "2005" @default.
- W2085202354 type Work @default.
- W2085202354 sameAs 2085202354 @default.
- W2085202354 citedByCount "27" @default.
- W2085202354 countsByYear W20852023542013 @default.
- W2085202354 countsByYear W20852023542014 @default.
- W2085202354 countsByYear W20852023542016 @default.
- W2085202354 countsByYear W20852023542018 @default.
- W2085202354 countsByYear W20852023542019 @default.
- W2085202354 countsByYear W20852023542021 @default.
- W2085202354 countsByYear W20852023542022 @default.
- W2085202354 crossrefType "journal-article" @default.
- W2085202354 hasAuthorship W2085202354A5013536350 @default.
- W2085202354 hasAuthorship W2085202354A5017836479 @default.
- W2085202354 hasAuthorship W2085202354A5020699066 @default.
- W2085202354 hasAuthorship W2085202354A5025900332 @default.
- W2085202354 hasAuthorship W2085202354A5043336909 @default.
- W2085202354 hasAuthorship W2085202354A5055488463 @default.
- W2085202354 hasAuthorship W2085202354A5071902523 @default.
- W2085202354 hasAuthorship W2085202354A5073724423 @default.
- W2085202354 hasAuthorship W2085202354A5074869230 @default.
- W2085202354 hasAuthorship W2085202354A5080908711 @default.
- W2085202354 hasAuthorship W2085202354A5082271642 @default.
- W2085202354 hasAuthorship W2085202354A5088816728 @default.
- W2085202354 hasConcept C185592680 @default.
- W2085202354 hasConcept C203014093 @default.
- W2085202354 hasConcept C26865036 @default.
- W2085202354 hasConcept C2776125364 @default.
- W2085202354 hasConcept C2776151105 @default.
- W2085202354 hasConcept C2776557347 @default.
- W2085202354 hasConcept C2778452849 @default.
- W2085202354 hasConcept C2778917026 @default.
- W2085202354 hasConcept C2778979269 @default.
- W2085202354 hasConcept C2779902561 @default.
- W2085202354 hasConcept C2780014101 @default.