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- W2085227479 abstract "La névrite optique est un effet indésirable rare de la vaccination antigrippale. Une patiente de 62 ans aux antécédents de syndrome de Sharp a présenté une névrite optique rétrobulbaire cécitante bilatérale 15 jours après une vaccination contre la grippe saisonnière. Le bilan étiologique ne retrouvait aucune cause évidente et compte tenu du délai de survenu, l’hypothèse d’une névrite optique post-vaccinale a été privilégiée. Nous n’avons cependant pas écarté l’hypothèse d’une complication de sa connectivite connue en dépit de la stabilité de celle-ci depuis plusieurs années. À ce jour, peu de cas identiques ont été décrits dans la littérature et, bien que le lien de causalité ne puisse être formellement conclu, cet effet indésirable doit toujours être envisagé. Optic neuropathy is a rare adverse reaction to vaccination. A 62-year-old-woman was hospitalized for bilateral optic neuropathy with loss of vision. The symptoms occurred 15 days after a seasonal influenza vaccination. Her past medical history included a mixed connective tissue disease with no immunosuppressive treatment for several years. Investigations did not reveal any obvious cause and the hypothesis of post-influenza vaccination bilateral optic neuropathy was retained although a complication of the connective tissue disease complication could not be ruled out. The patient was given intravenous methylprednisolone 1 g daily. At a cumulative dose of 8 g, oral steroids were given and tapered off. Few similar case reports have been described in literature. The causal link between vaccination and optic neuropathy thus remains to be confirmed. Clinicians should however consider this etiology." @default.
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- W2085227479 date "2010-12-01" @default.
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- W2085227479 title "Névrite optique rétrobulbaire bilatérale cécitante après vaccination contre la grippe saisonnière chez une patiente présentant un syndrome de Sharp" @default.
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- W2085227479 doi "https://doi.org/10.1016/j.neurol.2010.07.037" @default.
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