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- W2085234899 abstract "γ-Secretase is a key enzyme involved in the production of β-amyloid peptides which are believed to play a critical role in the onset and progression of Alzheimer’s disease (AD). As such, inhibition of γ-secretase has been an attractive approach to AD therapy. In this paper, the design, synthesis, and evaluation of tetrahydroquinoline and pyrrolidine sulfonamide carbamates as γ -secretase inhibitors are described." @default.
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- W2085234899 date "2007-06-01" @default.
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- W2085234899 title "Design, synthesis, and evaluation of tetrahydroquinoline and pyrrolidine sulfonamide carbamates as γ-secretase inhibitors" @default.
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- W2085234899 doi "https://doi.org/10.1016/j.bmcl.2007.03.055" @default.
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