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- W2085247353 abstract "Langmuir monolayers are often used as simple models for biological membranes. The possibility to change their composition and phase state in a very controlled manner as well as access to a large observation area makes them a versatile tool for the investigation of membrane-related interactions. Inspired by experiments in our group, we investigate the interaction of single, partially charged nanoparticles with lipid microdomains by Monte Carlo simulations. Condensed domains in inhomogeneous Langmuir monolayers exhibit an electric dipole field interacting attractively with the nanoparticle's dipole moment. With increasing domain size, the resulting electric field changes from single dipole to semi-infinite domain characteristics, significantly influencing the motion of the particle. Small immobile domains (R = 1 microm) confine the movement of the tracer to the boundary of the domain whereas for large domains (R > or = 10 microm) its motion is only temporarily hindered. This suggests a powerful mechanism for controlling diffusive transport in lipid membranes." @default.
- W2085247353 created "2016-06-24" @default.
- W2085247353 creator A5017365819 @default.
- W2085247353 creator A5072198137 @default.
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- W2085247353 date "2008-02-21" @default.
- W2085247353 modified "2023-09-23" @default.
- W2085247353 title "Diffusion of Nanoparticles in Monolayers is Modulated by Domain Size" @default.
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- W2085247353 doi "https://doi.org/10.1021/la703140b" @default.
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