Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085252134> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2085252134 abstract "The energy difference between the quaternary structures of deoxy- and oxyhemoglobin is evaluated on the basis of the atomic coordinates determined by X-ray diffraction analysis. Calculation of the van der Waals interaction between subunits shows that in a hemoglobin molecule as a whole, the interaction is more attractive in the oxy form than in the deoxy form by about 8 kcal/mol, and that in each pair of two subunits except the pair alpha1alpha2, the interaction energy varies by about 15 kcal/mol. The electrostatic interactions originating in the partial charges on all constituent atoms of hemoglobin and in the polar residues on the surface of hemoglobin make only a small contribution to the energy difference between the quaternary structures of deoxy- and oxyhemoglobin. Thus, the contribution of the clusters of the polar residues in the internal cavity between like subunits and also of the freedom of rotation of the C-terminal of each subunit in oxyhemoglobin may be important energetically in the transition from deoxy to oxy quaternary structure. In this point, the present calculation supports Perutz' model, but suggests necessity of further investigations on the transitional characteristics of the quaternary structure in the intermediate steps of oxygenation. The discussion on the transitional characteristics is given in the last section." @default.
- W2085252134 created "2016-06-24" @default.
- W2085252134 creator A5030014005 @default.
- W2085252134 creator A5052820654 @default.
- W2085252134 date "1975-10-01" @default.
- W2085252134 modified "2023-09-27" @default.
- W2085252134 title "Calculation of the energy difference between the quaternary structures of deoxy- and oxyhemoglobin" @default.
- W2085252134 cites W1518968170 @default.
- W2085252134 cites W1569553189 @default.
- W2085252134 cites W1974311257 @default.
- W2085252134 cites W1988311247 @default.
- W2085252134 cites W1998093640 @default.
- W2085252134 cites W2005392755 @default.
- W2085252134 cites W2023033606 @default.
- W2085252134 cites W2026911129 @default.
- W2085252134 cites W2027105538 @default.
- W2085252134 cites W2033004684 @default.
- W2085252134 cites W2047915087 @default.
- W2085252134 cites W2069002738 @default.
- W2085252134 cites W2073198049 @default.
- W2085252134 cites W2079503725 @default.
- W2085252134 cites W2080279820 @default.
- W2085252134 cites W2084781752 @default.
- W2085252134 cites W2135890946 @default.
- W2085252134 cites W230984257 @default.
- W2085252134 cites W2335253023 @default.
- W2085252134 cites W2616805578 @default.
- W2085252134 cites W285092801 @default.
- W2085252134 cites W2904832245 @default.
- W2085252134 cites W3119476946 @default.
- W2085252134 cites W4211189179 @default.
- W2085252134 cites W4248197743 @default.
- W2085252134 doi "https://doi.org/10.1016/0005-2795(75)90104-x" @default.
- W2085252134 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1237318" @default.
- W2085252134 hasPublicationYear "1975" @default.
- W2085252134 type Work @default.
- W2085252134 sameAs 2085252134 @default.
- W2085252134 citedByCount "9" @default.
- W2085252134 crossrefType "journal-article" @default.
- W2085252134 hasAuthorship W2085252134A5030014005 @default.
- W2085252134 hasAuthorship W2085252134A5052820654 @default.
- W2085252134 hasConcept C104292427 @default.
- W2085252134 hasConcept C104317684 @default.
- W2085252134 hasConcept C121332964 @default.
- W2085252134 hasConcept C126061179 @default.
- W2085252134 hasConcept C1276947 @default.
- W2085252134 hasConcept C147597530 @default.
- W2085252134 hasConcept C151730666 @default.
- W2085252134 hasConcept C159467904 @default.
- W2085252134 hasConcept C160464908 @default.
- W2085252134 hasConcept C178790620 @default.
- W2085252134 hasConcept C185592680 @default.
- W2085252134 hasConcept C2776403692 @default.
- W2085252134 hasConcept C2779546866 @default.
- W2085252134 hasConcept C29705727 @default.
- W2085252134 hasConcept C32909587 @default.
- W2085252134 hasConcept C55493867 @default.
- W2085252134 hasConcept C71240020 @default.
- W2085252134 hasConcept C7927669 @default.
- W2085252134 hasConcept C8010536 @default.
- W2085252134 hasConcept C86803240 @default.
- W2085252134 hasConceptScore W2085252134C104292427 @default.
- W2085252134 hasConceptScore W2085252134C104317684 @default.
- W2085252134 hasConceptScore W2085252134C121332964 @default.
- W2085252134 hasConceptScore W2085252134C126061179 @default.
- W2085252134 hasConceptScore W2085252134C1276947 @default.
- W2085252134 hasConceptScore W2085252134C147597530 @default.
- W2085252134 hasConceptScore W2085252134C151730666 @default.
- W2085252134 hasConceptScore W2085252134C159467904 @default.
- W2085252134 hasConceptScore W2085252134C160464908 @default.
- W2085252134 hasConceptScore W2085252134C178790620 @default.
- W2085252134 hasConceptScore W2085252134C185592680 @default.
- W2085252134 hasConceptScore W2085252134C2776403692 @default.
- W2085252134 hasConceptScore W2085252134C2779546866 @default.
- W2085252134 hasConceptScore W2085252134C29705727 @default.
- W2085252134 hasConceptScore W2085252134C32909587 @default.
- W2085252134 hasConceptScore W2085252134C55493867 @default.
- W2085252134 hasConceptScore W2085252134C71240020 @default.
- W2085252134 hasConceptScore W2085252134C7927669 @default.
- W2085252134 hasConceptScore W2085252134C8010536 @default.
- W2085252134 hasConceptScore W2085252134C86803240 @default.
- W2085252134 hasLocation W20852521341 @default.
- W2085252134 hasLocation W20852521342 @default.
- W2085252134 hasOpenAccess W2085252134 @default.
- W2085252134 hasPrimaryLocation W20852521341 @default.
- W2085252134 hasRelatedWork W1963973149 @default.
- W2085252134 hasRelatedWork W2005831018 @default.
- W2085252134 hasRelatedWork W2037332327 @default.
- W2085252134 hasRelatedWork W2069853948 @default.
- W2085252134 hasRelatedWork W2322592617 @default.
- W2085252134 hasRelatedWork W2406017546 @default.
- W2085252134 hasRelatedWork W2914451151 @default.
- W2085252134 hasRelatedWork W3015532053 @default.
- W2085252134 hasRelatedWork W3022296595 @default.
- W2085252134 hasRelatedWork W3207571903 @default.
- W2085252134 isParatext "false" @default.
- W2085252134 isRetracted "false" @default.
- W2085252134 magId "2085252134" @default.
- W2085252134 workType "article" @default.